For professionals in the pharmaceutical and chemical industries, sourcing high-quality raw materials is paramount. D-Mannitol, identified by CAS number 69-65-8, stands out as a critical ingredient, particularly valued for its role as a pharmaceutical excipient and a natural sweetener. Understanding its properties and the best practices for procurement can significantly impact product development and manufacturing efficiency. This guide aims to provide insights into D-Mannitol, focusing on aspects relevant to procurement managers, R&D scientists, and formulation chemists.

D-Mannitol is a hexitol, a type of sugar alcohol, naturally found in various plants and fungi. It typically presents as a white crystalline powder, noted for its pleasant, sweet taste with about 50-70% the sweetness of sucrose. Its low hygroscopicity is a key advantage, making it an excellent choice for direct compression in tablet manufacturing, preventing issues like caking and moisture absorption that can affect product stability. This property makes it a preferred diluent and bulking agent in many oral dosage forms.

As a pharmaceutical excipient, D-Mannitol offers several benefits. Its inertness and excellent compressibility contribute to the robustness of tablet formulations. Beyond its physical properties, its taste-masking capabilities can improve the palatability of medications, a crucial factor for patient compliance, especially in pediatric or geriatric formulations. Many manufacturers seek D-Mannitol for its ability to improve flow properties and provide a smooth mouthfeel in chewable tablets or orally disintegrating tablets.

When looking to buy D-Mannitol pharmaceutical grade, emphasis should be placed on purity and adherence to regulatory standards. Reputable suppliers will offer D-Mannitol with a purity exceeding 99%, meeting pharmacopeial requirements such as USP (United States Pharmacopeia) and BP (British Pharmacopoeia). These standards ensure the absence of harmful impurities and guarantee consistent performance in sensitive pharmaceutical applications. It is essential to request Certificates of Analysis (CoA) from your D-Mannitol supplier in China to verify these specifications.

For those managing budgets and supply chains, understanding the D-Mannitol price per kg is vital. Direct sourcing from a D-Mannitol manufacturer often yields more competitive pricing compared to distributors. Manufacturers can provide detailed quotes for bulk quantities, allowing for better cost management. When inquiring about pricing, be sure to specify the required grade, quantity, and any specific packaging needs.

The search for a reliable D-Mannitol manufacturer requires due diligence. Look for suppliers with established quality management systems, such as ISO certifications and GMP compliance. A strong track record in exporting pharmaceutical raw materials, coupled with responsive customer service and efficient logistics, indicates a trustworthy partner. Companies specializing in bulk pharmaceutical ingredients can provide not only the product but also the necessary technical support and regulatory documentation required for drug development.

In summary, D-Mannitol is an indispensable ingredient for many pharmaceutical products. By focusing on purity, regulatory compliance, and a reliable supply chain, businesses can secure high-quality D-Mannitol to enhance their formulations. Whether you are researching D-Mannitol for tablet formulation or seeking competitive D-Mannitol manufacturer quote, partnering with a reputable supplier ensures product integrity and manufacturing success.