Daidzin Applications: From Antioxidants to ALDH2 Inhibition
Daidzin, a naturally occurring isoflavone glucoside identified by CAS number 552-66-9, is a compound of considerable interest across various scientific and industrial sectors. Its unique chemical structure and biological activities make it a valuable ingredient for research and development, particularly in the fields of health, medicine, and biochemistry. Understanding the breadth of Daidzin applications is key for researchers and procurement specialists looking to leverage its potential. As a leading supplier of Daidzin, we are pleased to highlight its diverse uses.
One of the most well-documented properties of Daidzin is its antioxidant capacity. Like many flavonoids, Daidzin can help neutralize harmful free radicals within the body, thereby mitigating oxidative stress. Oxidative stress is implicated in a wide range of chronic diseases and aging processes, making antioxidant compounds like Daidzin subjects of ongoing research in nutraceuticals and preventative health. For those in this sector, sourcing high-purity Daidzin for research and product formulation is a primary objective.
Perhaps Daidzin's most specific and potent application lies in its role as an inhibitor of human mitochondrial aldehyde dehydrogenase 2 (ALDH2). With a reported IC50 of 80 nM for ALDH2, Daidzin is a powerful selective inhibitor. ALDH2 is crucial for metabolizing aldehydes, including acetaldehyde, a toxic byproduct of ethanol metabolism. Research into ALDH2 inhibitors like Daidzin is exploring potential therapeutic strategies for alcohol-related disorders, as well as other conditions where ALDH2 activity is relevant. This makes Daidzin an invaluable tool for biochemical research and a potential pharmaceutical intermediate.
Beyond these primary functions, Daidzin has also shown promise in chemoprevention research. Studies suggest it can inhibit the bioactivation of certain carcinogenic arylamines, potentially reducing cancer risk. Its influence on cellular pathways, such as inhibiting the JAK2/STAT3 pathway in cervical cancer cells or interfering with the glycolytic pathway in hepatocellular carcinoma, is also an active area of investigation. These findings highlight Daidzin's potential as a lead compound for developing novel therapeutics. For researchers and pharmaceutical companies, buying Daidzin from a reliable supplier ensures access to material suitable for these advanced studies.
In summary, the applications of Daidzin (CAS 552-66-9) are extensive and scientifically significant. From its fundamental antioxidant properties to its specific action as an ALDH2 inhibitor and its potential in chemoprevention, Daidzin offers a wealth of research opportunities. We are proud to be a dedicated manufacturer and supplier of high-quality Daidzin, supporting the scientific community with a reliable source for this versatile compound.
Perspectives & Insights
Agile Reader One
“Oxidative stress is implicated in a wide range of chronic diseases and aging processes, making antioxidant compounds like Daidzin subjects of ongoing research in nutraceuticals and preventative health.”
Logic Vision Labs
“For those in this sector, sourcing high-purity Daidzin for research and product formulation is a primary objective.”
Molecule Origin 88
“Perhaps Daidzin's most specific and potent application lies in its role as an inhibitor of human mitochondrial aldehyde dehydrogenase 2 (ALDH2).”