In the realm of organic chemistry, selective functional group protection is a fundamental strategy for achieving complex molecular targets. Di-tert-butyl dicarbonate (CAS 24424-99-5), commonly known as Boc anhydride, stands out as a premier reagent for the protection of amine functionalities. Its widespread adoption in research and industry is a testament to its efficiency, reliability, and the valuable properties it imparts to synthetic pathways. As a professional manufacturer and supplier, we are dedicated to providing access to this essential chemical.

The mechanism by which Di-tert-butyl dicarbonate protects amines involves a straightforward reaction where the amine nucleophilically attacks one of the carbonyl carbons of the anhydride. This results in the formation of a stable tert-butoxycarbonyl (Boc) derivative and the release of tert-butanol and carbon dioxide upon subsequent decomposition. This method is highly effective for both primary and secondary amines, forming stable carbamates that are inert to many common reagents used in subsequent synthetic steps. The Boc group's characteristic lability under acidic conditions (e.g., using trifluoroacetic acid) allows for its selective removal, enabling controlled synthesis. This makes it a go-to reagent for anyone looking to buy Boc anhydride for their laboratory needs.

The versatility of Boc anhydride extends across various fields, from peptide synthesis, where it is crucial for building amino acid chains, to the preparation of pharmaceutical intermediates and fine chemicals. For those seeking a dependable source, we offer Di-tert-butyl dicarbonate with guaranteed high purity and competitive prices. As a leading supplier in China, we ensure that our clients can readily purchase this critical reagent to support their research and development or manufacturing operations. Explore the advantages of integrating our Di-tert-butyl dicarbonate into your synthetic workflows.