Diethyl Isopropylmalonate: A Key Intermediate for Pharmaceutical Manufacturers
The pharmaceutical industry relies heavily on a consistent supply of high-purity chemical intermediates to drive drug discovery and manufacturing processes. Diethyl Isopropylmalonate (CAS: 759-36-4) is one such vital compound, serving as a versatile building block in the synthesis of active pharmaceutical ingredients (APIs) and related compounds. For pharmaceutical manufacturers, understanding the specifications, applications, and sourcing of this chemical is critical for operational success.
Chemical Profile and Quality Assurance
Diethyl Isopropylmalonate, identified by CAS number 759-36-4, is supplied as a colorless liquid. Its molecular formula is C10H18O4, and it has a molecular weight of 202.25. Manufacturers typically guarantee a purity level of 97% or higher (GC), ensuring that the material is suitable for sensitive pharmaceutical synthesis. Critical properties such as boiling point (62 °C/0.35 mmHg) and density (0.981 g/mL at 25 °C) are meticulously controlled to guarantee batch-to-batch consistency. This commitment to quality is non-negotiable for pharmaceutical applications where precise molecular structure and purity are paramount. When you buy Diethyl Isopropylmalonate, always verify the Certificate of Analysis (CoA) from your supplier.
Critical Applications in Pharmaceutical Synthesis
As a malonate ester derivative, Diethyl Isopropylmalonate is a key intermediate in various organic synthesis routes. Its utility extends to the creation of complex molecular architectures required for pharmaceutical compounds. Specifically, its application in the synthesis of compounds for treating CCR2-mediated diseases is an area of growing interest within the medical research community. Pharmaceutical manufacturers can leverage this intermediate to streamline their synthesis pathways, reduce reaction steps, and improve overall yield efficiency. For those in drug manufacturing, buying this reagent means investing in a proven synthetic tool.
Strategic Sourcing and Supplier Relationships
Identifying reliable manufacturers and suppliers for Diethyl Isopropylmalonate is a strategic imperative for pharmaceutical companies. China is a global leader in chemical manufacturing, offering numerous sources for this intermediate. When selecting a supplier, it is essential to prioritize those with established quality management systems and a proven track record in supplying the pharmaceutical sector. Factors such as pricing, minimum order quantities, and delivery lead times should also be carefully evaluated. For bulk purchases, negotiating favorable terms with your manufacturer can significantly impact cost-effectiveness. We encourage you to request a quote to explore how NINGBO INNO PHARMCHEM CO.,LTD. can fulfill your procurement needs for this critical intermediate.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing the pharmaceutical industry with high-quality chemical intermediates. Our focus on purity, reliability, and competitive pricing makes us a preferred partner for manufacturers seeking to buy Diethyl Isopropylmalonate.
Perspectives & Insights
Data Seeker X
“Chemical Profile and Quality Assurance Diethyl Isopropylmalonate, identified by CAS number 759-36-4, is supplied as a colorless liquid.”
Chem Reader AI
“Manufacturers typically guarantee a purity level of 97% or higher (GC), ensuring that the material is suitable for sensitive pharmaceutical synthesis.”
Agile Vision 2025
“981 g/mL at 25 °C) are meticulously controlled to guarantee batch-to-batch consistency.”