Dipeptide Synthesis: The Role of Phenylalanyl Alanine in Peptide Chemistry
Peptide chemistry is a sophisticated field that underpins much of modern biological and pharmaceutical research. Peptides, short chains of amino acids linked by peptide bonds, play crucial roles in countless biological processes and are increasingly utilized as therapeutic agents. At the heart of peptide synthesis lies the strategic use of individual amino acids and small peptide fragments, such as dipeptides, as building blocks. One such significant dipeptide is (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid, also known by its CAS number 3918-87-4.
This specific dipeptide is formed from the coupling of L-phenylalanine and L-alanine, two fundamental amino acids. Its structure, C12H16N2O3, and molecular weight of 236.27 g/mol are critical parameters for its use in synthetic peptide chemistry. The 'S' designation for both amino acid residues highlights its specific stereochemistry, which is vital for the biological activity and structural integrity of the resulting larger peptides.
In peptide synthesis, dipeptides like (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid can be employed in several ways. They can be used to accelerate the synthesis process by introducing two amino acids at once, thereby reducing the number of coupling steps required. This can lead to higher overall yields and a purer final peptide product. Furthermore, utilizing pre-formed dipeptides can help overcome challenges associated with the synthesis of certain peptide sequences that might be difficult to assemble step-by-step.
The chemical industry, particularly manufacturers in China, plays a pivotal role in supplying these essential peptide synthesis reagents. The availability of high-purity (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid allows researchers to focus on the design and assembly of novel peptide structures for various applications, ranging from drug development to materials science. The compound's white solid appearance and defined melting point (241°C) are indicative of its quality and suitability for demanding chemical reactions.
The strategic incorporation of dipeptides into synthetic routes is a hallmark of efficient peptide chemistry. By leveraging compounds like (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid, scientists can more effectively explore the vast chemical space of peptides, leading to the discovery of new biomolecules with enhanced therapeutic properties or novel material functionalities. As research in peptide-based therapeutics continues to expand, the demand for high-quality dipeptide building blocks from reliable suppliers will undoubtedly grow.
This specific dipeptide is formed from the coupling of L-phenylalanine and L-alanine, two fundamental amino acids. Its structure, C12H16N2O3, and molecular weight of 236.27 g/mol are critical parameters for its use in synthetic peptide chemistry. The 'S' designation for both amino acid residues highlights its specific stereochemistry, which is vital for the biological activity and structural integrity of the resulting larger peptides.
In peptide synthesis, dipeptides like (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid can be employed in several ways. They can be used to accelerate the synthesis process by introducing two amino acids at once, thereby reducing the number of coupling steps required. This can lead to higher overall yields and a purer final peptide product. Furthermore, utilizing pre-formed dipeptides can help overcome challenges associated with the synthesis of certain peptide sequences that might be difficult to assemble step-by-step.
The chemical industry, particularly manufacturers in China, plays a pivotal role in supplying these essential peptide synthesis reagents. The availability of high-purity (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid allows researchers to focus on the design and assembly of novel peptide structures for various applications, ranging from drug development to materials science. The compound's white solid appearance and defined melting point (241°C) are indicative of its quality and suitability for demanding chemical reactions.
The strategic incorporation of dipeptides into synthetic routes is a hallmark of efficient peptide chemistry. By leveraging compounds like (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid, scientists can more effectively explore the vast chemical space of peptides, leading to the discovery of new biomolecules with enhanced therapeutic properties or novel material functionalities. As research in peptide-based therapeutics continues to expand, the demand for high-quality dipeptide building blocks from reliable suppliers will undoubtedly grow.
Perspectives & Insights
Molecule Vision 7
“Peptides, short chains of amino acids linked by peptide bonds, play crucial roles in countless biological processes and are increasingly utilized as therapeutic agents.”
Alpha Origin 24
“At the heart of peptide synthesis lies the strategic use of individual amino acids and small peptide fragments, such as dipeptides, as building blocks.”
Future Analyst X
“One such significant dipeptide is (S)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid, also known by its CAS number 3918-87-4.”