Diphenhydramine Hydrochloride (CAS 147-24-0) is a versatile chemical compound with significant applications, particularly in the pharmaceutical industry. As a key ingredient in many over-the-counter medications, understanding its properties and the quality standards expected from manufacturers and suppliers is vital for any procurement professional or formulator.

The primary application of Diphenhydramine Hydrochloride is as an active ingredient in antihistamines. It functions by blocking the action of histamine, a substance in the body that causes allergic symptoms. This makes it effective in treating conditions such as hay fever, allergies, the common cold, and symptoms of motion sickness. Its anticholinergic properties also contribute to its use in some sleep aids and as a mild sedative.

For those looking to buy Diphenhydramine Hydrochloride, maintaining high quality is non-negotiable. Reputable manufacturers, particularly those based in China, emphasize strict quality control throughout the production process. Key quality indicators to look for include a fine, white crystalline powder appearance, a specified melting point range (typically around 169-170 °C), and high purity, often exceeding 99%. A detailed Certificate of Analysis (CoA) from the supplier is essential to verify these parameters and ensure compliance with pharmacopoeial standards.

When sourcing this compound, consider its molecular formula (C17H21NO.HCl) and molecular weight (291.85). These details are important for formulation calculations. Engaging with suppliers who can provide consistent product batches and reliable documentation is crucial for uninterrupted production cycles.

In summary, Diphenhydramine Hydrochloride is a vital pharmaceutical intermediate. By focusing on its applications and demanding adherence to stringent quality standards from your chemical suppliers, you can ensure the efficacy and safety of your end products.