For professionals engaged in the intricate field of peptide synthesis, sourcing high-quality building blocks is paramount. DL-Pyroglutamic Acid, identified by CAS number 149-87-1, stands out as a versatile and indispensable intermediate. As a leading manufacturer and supplier based in China, we understand the critical need for purity and consistency in your chemical reagents. This article delves into why DL-Pyroglutamic Acid is a preferred choice for peptide synthesis and how our company can meet your procurement demands.

Understanding DL-Pyroglutamic Acid

DL-Pyroglutamic Acid, also known by synonyms such as 2-Pyrrolidone-5-carboxylic Acid, is a cyclic derivative of glutamic acid. Its unique structure makes it an excellent starting material or intermediate in the synthesis of a wide array of complex molecules. Chemically, it presents as a white crystalline powder with a melting point typically between 180-185°C and a purity exceeding 98%. This high purity is crucial for ensuring successful and reproducible results in peptide synthesis, where even trace impurities can compromise the final product.

Applications in Peptide Synthesis

The primary utility of DL-Pyroglutamic Acid in peptide synthesis lies in its ability to introduce specific structural elements and modify peptide sequences. It can be incorporated into peptide chains to influence their conformation, stability, and biological activity. For instance, the pyroglutamate N-terminus is a common feature in naturally occurring peptides and proteins, often serving to protect them from enzymatic degradation. Researchers and manufacturers rely on suppliers like us to provide this essential amino acid derivative in bulk quantities, ensuring a stable supply for ongoing projects.

Beyond Peptide Synthesis: Pharmaceutical and Biochemical Roles

While its role in peptide synthesis is significant, DL-Pyroglutamic Acid also finds critical applications as a pharmaceutical intermediate. It is notably used in the preparation of AZT steroid conjugates, which have demonstrated potency as anti-HIV agents. Furthermore, its involvement in the gamma-glutamyl cycle, essential for glutathione production and recycling, highlights its importance as a biochemical reagent. Understanding its biological functions can open new avenues for research and development in areas like antioxidant therapy and metabolic pathway modulation.

Why Choose Our DL-Pyroglutamic Acid?

As a dedicated manufacturer and supplier in China, we pride ourselves on offering DL-Pyroglutamic Acid that meets rigorous quality standards. Our commitment extends beyond product quality; we aim to be a reliable partner for all your chemical procurement needs. When you choose to buy DL-Pyroglutamic Acid from us, you benefit from:

  • Guaranteed High Purity: Ensuring your synthesis projects yield superior results.
  • Competitive Manufacturer Pricing: Accessing cost-effective solutions without compromising on quality.
  • Stable Supply Chain: Benefiting from our consistent production capacity and efficient logistics.
  • Responsive Customer Service: Promptly addressing your inquiries and providing technical support.

We cater to both small-scale research needs and large-volume industrial demands. If you are looking to purchase DL-Pyroglutamic Acid or require a detailed quote, please do not hesitate to contact our sales team. We are eager to support your scientific endeavors and manufacturing processes.