Pregnancy often brings a host of challenges, with nausea and vomiting being among the most common. For pharmaceutical companies and formulators, understanding the ingredients used to manage these symptoms is critical. Doxylamine Succinate (CAS 562-10-7) has emerged as a significant compound in this area, often used in combination therapies. NINGBO INNO PHARMCHEM CO.,LTD., a dedicated doxylamine succinate manufacturer and supplier in China, offers high-purity material essential for these formulations. This article explores the role of Doxylamine Succinate in pregnancy and provides insights valuable for industry professionals.

Understanding Nausea and Vomiting of Pregnancy (NVP)

Nausea and vomiting of pregnancy, commonly known as morning sickness, can range from mild discomfort to severe debilitation (hyperemesis gravidarum). While lifestyle and dietary changes can help manage milder cases, some individuals require pharmacological intervention. Historically, various treatments have been employed, with a focus on safety and efficacy for both the mother and the developing fetus.

Doxylamine Succinate: A Key Pharmaceutical Intermediate

Doxylamine Succinate, a first-generation antihistamine, possesses anticholinergic properties that are believed to contribute to its effectiveness in alleviating nausea and vomiting. It works by blocking the effects of histamine and acetylcholine in the body, which can influence the vomiting reflex. Its use in pregnancy is often in combination with Vitamin B6 (pyridoxine hydrochloride), a well-established approach to managing NVP. This combination has undergone significant study, with regulatory bodies like the FDA generally recognizing its safety for use in pregnant women when prescribed appropriately.

Safety Profile and Regulatory Considerations

For formulators and procurement managers, the safety profile of any API is paramount, especially when intended for use in pregnant women. Extensive epidemiological studies have been conducted on Doxylamine Succinate, particularly in combination with pyridoxine. While historical controversies existed regarding teratogenicity, current consensus and regulatory reviews generally indicate that it is unlikely to cause birth defects when used as directed. However, it is crucial for healthcare providers to assess individual risks and benefits. As a reputable doxylamine succinate supplier, we ensure our product meets the highest purity standards, supporting the safety and efficacy of your finished products.

Procurement for Pharmaceutical Formulations

Companies looking to buy doxylamine succinate for NVP treatments or other pharmaceutical applications should prioritize sourcing from reliable manufacturers. Our position as a leading doxylamine succinate manufacturer in China allows us to offer competitive doxylamine succinate prices while maintaining stringent quality control. We supply pharmaceutical-grade material suitable for diverse formulation needs. Whether you require small quantities for R&D or bulk orders for commercial production, our supply chain is robust and dependable. We encourage inquiries to explore our product specifications and to discuss your specific sourcing requirements.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the pharmaceutical industry with essential, high-quality chemical intermediates. By choosing us as your doxylamine succinate supplier, you gain access to a product that plays a vital role in maternal healthcare, backed by our commitment to quality and service.