N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, more commonly known as EEDQ (CAS 16357-59-8), is a specialized organic chemical that plays a critical role in various scientific and industrial applications, most notably in organic synthesis and pharmaceutical development. Its utility as a condensation reagent, particularly for peptide synthesis, has cemented its place as a valuable compound in laboratories worldwide.

The compound presents itself as an off-white to white crystalline powder, with a defined melting point range of 62-67°C. Its molecular formula, C14H17NO3, and molecular weight of 247.29 g/mol are standard parameters that researchers rely on. A key attribute that makes EEDQ highly sought after is its purity, typically guaranteed at ≥99.0% by HPLC. This high level of purity is essential for ensuring the accuracy and reliability of synthetic reactions, especially in the intricate processes of peptide bond formation where stereochemical control is vital.

The primary application of EEDQ is as a condensation reagent in peptide synthesis. It facilitates the coupling of amino and carboxyl groups, enabling the formation of amide bonds with significantly reduced risk of racemization. This property is crucial for synthesizing biologically active peptides, which are increasingly used in therapeutics and diagnostics. Researchers often cite EEDQ as a preferred choice due to its efficiency and the high quality of the resulting peptide products.

Beyond peptide synthesis, EEDQ also serves as an irreversible membrane-bound receptor antagonist, indicating its potential use in pharmacological research and drug discovery. This dual functionality makes it a versatile compound for chemists and biologists alike.

For businesses looking to buy EEDQ, particularly from China, understanding the market and identifying reliable sources is key. Many manufacturers and suppliers in China offer this compound, ensuring competitive pricing and readily available stock. When selecting a N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline supplier, prioritize those who provide detailed specifications, Certificates of Analysis (CoA), and responsive customer support. Whether you need small quantities for research or bulk orders for production, a dependable EEDQ manufacturer is essential for your supply chain.