Elacridar (GF120918): A Versatile Tool for Neuroscience Research
Neuroscience research presents unique challenges, particularly in delivering therapeutic agents effectively across the formidable blood-brain barrier (BBB). The BBB acts as a critical gatekeeper, protecting the brain but also restricting the passage of many potential treatments for neurological disorders. P-glycoprotein (P-gp), a prominent efflux transporter located at the BBB, plays a significant role in limiting the brain accumulation of numerous drugs. Elacridar, a potent P-gp inhibitor, offers a vital solution for researchers in this field.
Elacridar, also known by its research code GF120918 and CAS number 143664-11-3, is a potent and selective inhibitor of P-gp. Its capacity to block P-gp-mediated efflux makes it an indispensable tool for scientists investigating drug transport at the BBB. By inhibiting P-gp, Elacridar allows drugs that are normally expelled from brain endothelial cells to remain within the brain tissue, thereby increasing their concentration and therapeutic potential. This mechanism is crucial for developing effective treatments for conditions like Alzheimer's disease, Parkinson's disease, and brain tumors.
For neuroscience researchers, sourcing high-quality Elacridar is essential for obtaining reliable experimental results. We, as a reputable manufacturer and supplier of Elacridar in China, provide access to this critical research chemical with guaranteed high purity. When you choose to buy Elacridar from us, you are ensuring the quality and consistency needed for complex neuroscience studies. Our product is instrumental in experiments designed to understand drug disposition in the brain and to identify compounds with improved BBB permeability.
The versatility of Elacridar extends to its use in combination with various CNS-active drugs. Researchers often combine Elacridar with potential therapeutics to assess the impact on brain uptake and efficacy. This approach helps in identifying drug candidates with a better therapeutic index and in designing optimized dosing strategies. Purchasing Elacridar for your neuroscience projects can significantly advance your understanding of drug-target interactions and the development of novel neurotherapeutics. We encourage you to reach out for quotes and inquire about bulk purchase options to support your ongoing research.
In summary, Elacridar (GF120918) is a cornerstone in neuroscience research for overcoming BBB drug efflux. As a trusted supplier, we are committed to providing researchers with the high-quality Elacridar needed to unlock new therapeutic possibilities for brain disorders. Partner with us to secure your supply and advance your critical research.
Perspectives & Insights
Quantum Pioneer 24
“This mechanism is crucial for developing effective treatments for conditions like Alzheimer's disease, Parkinson's disease, and brain tumors.”
Bio Explorer X
“For neuroscience researchers, sourcing high-quality Elacridar is essential for obtaining reliable experimental results.”
Nano Catalyst AI
“We, as a reputable manufacturer and supplier of Elacridar in China, provide access to this critical research chemical with guaranteed high purity.”