Multidrug resistance (MDR) remains a formidable challenge in cancer chemotherapy, significantly limiting the effectiveness of many life-saving drugs. Cancer cells can develop mechanisms to expel chemotherapeutic agents, rendering treatments ineffective. Understanding and combating these efflux pumps is crucial for advancing cancer therapy. This is where potent inhibitors like Elacridar come into play.

Elacridar, identified by CAS number 143664-11-3, is a highly regarded research chemical and pharmaceutical intermediate recognized for its powerful inhibitory effects on P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). These proteins are key players in the MDR phenomenon, actively pumping cytotoxic drugs out of cancer cells. By blocking the action of P-gp and BCRP, Elacridar allows chemotherapeutic agents to accumulate within cancer cells, thereby enhancing their cytotoxic activity and potentially restoring sensitivity to treatments.

For researchers and pharmaceutical developers, securing a reliable source of high-quality Elacridar is paramount. As a leading manufacturer and supplier of Elacridar in China, we are dedicated to providing products that meet stringent purity standards (typically ≥98%). This ensures that your experimental results are accurate and reproducible. Whether you are investigating novel combination therapies, exploring drug delivery systems, or conducting fundamental research on transporter mechanisms, our Elacridar can be a critical component in your arsenal.

The benefits of integrating Elacridar into your research workflow are substantial. It has been shown to enhance the brain penetration of certain drugs, making it a valuable tool for neuroscience research and the development of central nervous system (CNS) therapies. Furthermore, its ability to reverse resistance in various cancer models makes it a key intermediate for drug discovery programs aiming to improve patient outcomes. Researchers often seek to buy Elacridar to improve the bioavailability and efficacy of their test compounds, thereby reducing the required dosages and potentially mitigating side effects.

When considering your next purchase, remember that sourcing from a reputable manufacturer in China offers competitive pricing without compromising on quality. We understand the importance of a stable supply chain for critical research chemicals. We encourage you to contact us for a quote on Elacridar, explore our bulk purchase options, and request samples to evaluate our product's performance in your specific applications. Empower your cancer research and drug development with Elacridar – your reliable partner in overcoming resistance.