In the dynamic field of protein engineering, the ability to precisely modify protein structures and functions is paramount. Unnatural amino acids have emerged as powerful tools for researchers seeking to expand the chemical repertoire of proteins. Among these, 4-Iodo-L-phenylalanine (CAS 24250-85-9) stands out as a versatile building block, enabling novel advancements in areas from drug discovery to materials science.

As a leading manufacturer and supplier of fine chemicals, we recognize the growing demand for high-quality unnatural amino acids. 4-Iodo-L-phenylalanine offers researchers a unique opportunity to incorporate an iodinated phenyl ring into the amino acid backbone. This modification is particularly valuable in protein engineering for several key reasons:

  • Site-Specific Incorporation: It can be incorporated into proteins using established genetic code expansion techniques, allowing scientists to introduce specific functionalities at targeted sites within a protein sequence. This precision is crucial for understanding protein-protein interactions and designing novel enzymes.
  • Platform for Further Modification: The iodine atom on the phenyl ring serves as a convenient handle for subsequent chemical modifications. Researchers can perform palladium-catalyzed cross-coupling reactions, such as Suzuki or Sonogashira couplings, to attach a wide array of other functional groups, thereby creating highly customized proteins.
  • Radiolabeling and Imaging: The presence of iodine makes this amino acid amenable to radiolabeling with radioactive isotopes of iodine. This capability is invaluable for developing diagnostic imaging agents or for tracking protein localization and metabolism within biological systems.

When considering the purchase of 4-Iodo-L-phenylalanine, it is essential to source from a reliable manufacturer and supplier to ensure purity and consistency. Our commitment as a supplier in China guarantees that researchers receive a product meeting stringent quality standards (typically 98% HPLC purity). This reliability is non-negotiable for experiments that demand reproducibility and accuracy.

The applications extend beyond basic research. Pharmaceutical companies utilize such specialized amino acids in the development of targeted therapeutics and bioconjugates. The ability to precisely engineer proteins with enhanced properties or novel functions is driving innovation across the biotechnology sector. For those looking to buy this essential component, understanding its properties and the importance of a dependable supply chain is key.

To effectively integrate 4-Iodo-L-phenylalanine into your research, it's vital to consult detailed product specifications and follow recommended storage conditions, as many such compounds are light-sensitive. As your trusted supplier, we provide comprehensive technical information to facilitate its use. Exploring how to buy this crucial building block from us can unlock new possibilities in your protein engineering endeavors.