In the B2B chemical landscape, especially within the pharmaceutical and fine chemical sectors, precision and quality are non-negotiable. For critical intermediates like 1-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol (CAS 24155-42-8), a thorough understanding of its specifications is paramount for procurement managers, R&D scientists, and product formulators. This article delves into the key quality parameters that define this essential compound, ensuring buyers can make informed decisions when sourcing from manufacturers.

The primary role of 1-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol as a pharmaceutical intermediate, particularly for antifungal drugs like econazole and miconazole, places a high emphasis on its purity. The most commonly cited and critical specification is its chromatographic purity, usually determined by High-Performance Liquid Chromatography (HPLC). A high purity level, often specified as ≥99.0%, is essential to minimize the presence of related substances and impurities that could compromise the efficacy and safety of the final active pharmaceutical ingredient (API). When inquiring about the 1-(2,4-dichlorophenyl)-1h-imidazole-1-ethanol price, always verify the declared purity and the analytical method used.

The appearance of the compound is another straightforward yet important indicator of its quality. 1-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol is typically supplied as a white powder. Any deviation from this, such as discoloration (e.g., pale yellow or beige) or an unusual texture, might suggest issues with manufacturing, storage, or handling, and warrants further investigation by the buyer.

Beyond purity and appearance, several typical properties provide further insights into the chemical's characteristics and suitability for various applications:

  • Molecular Formula: C11H10Cl2N2O - This confirms the elemental composition.
  • Molecular Weight: 257.12 - Crucial for stoichiometric calculations in synthesis.
  • Melting Range: Typically cited between 133-138°C. A narrow melting range often indicates higher purity.
  • Loss on Drying: Usually ≤0.5%, indicating minimal residual solvent or moisture content.
  • Sulphated Ash: Typically ≤0.1%, reflecting low inorganic impurity levels.
  • Related Substances: Limits are set for specific known impurities (e.g., 1-(2,5-Dichlorophenyl)-2-(1H-Imidazole-1-yl)ethanol, 1-(3,4-Dichlorophenyl)-2-(1H-Imidazole-1-yl)ethanol, etc.), with individual limits often at ≤0.1% and the sum of impurities at ≤1.0%.
  • Potentiometric Assay: Generally specified between 98% and 101.0%, providing another measure of the active compound's content.

These specifications are not merely technical data points; they are the backbone of reliable chemical sourcing. For manufacturers seeking to buy 1-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol, partnering with a supplier that consistently delivers material meeting these stringent parameters is key. As a leading manufacturer and supplier, we are dedicated to adhering to these quality standards, ensuring that our customers receive intermediates that are fit for purpose, whether for complex pharmaceutical syntheses or other demanding industrial applications. Our commitment to transparency means providing comprehensive documentation and clear specifications for every batch we supply.