In the exacting world of chemical synthesis, particularly within the pharmaceutical sector, the specifications of starting materials are non-negotiable. 2-Methyl-2-propyl-1,3-propanediol (CAS 78-26-2) is a prime example of an intermediate where purity and consistent quality are paramount. For R&D scientists, quality control managers, and procurement specialists, a deep understanding of its key specifications is vital for successful sourcing and application.

Defining High-Purity 2-Methyl-2-propyl-1,3-propanediol

When sourcing 2-Methyl-2-propyl-1,3-propanediol, the most frequently cited specification is its purity level, often stated as ≥99.0% by Gas Chromatography (GC). This high degree of purity is essential for its primary uses as a pharmaceutical intermediate and a building block in organic synthesis. Impurities, even in trace amounts, can lead to unwanted side reactions, lower yields, or compromised efficacy in the final product, especially in pharmaceutical applications where regulatory compliance is stringent.

Key Specifications to Verify

  • Appearance: Typically described as a white or off-white solid. Any significant deviation in color or form might indicate contamination or degradation.
  • Assay (Purity): As mentioned, ≥99.0% is a common standard, often determined by GC. Other analytical methods like HPLC or titration might also be used depending on the supplier and customer requirements.
  • CAS Number: The CAS number 78-26-2 is the definitive identifier for this compound, ensuring you are sourcing the correct chemical entity.
  • Molecular Formula and Weight: C7H16O2 and a molecular weight of 132.2 g/mol are fundamental identifiers.
  • Physical Form: Described as a solid, often crystalline powder. The physical form can influence handling and dissolution characteristics.
  • Moisture Content: For some applications, residual moisture can be critical. Suppliers may specify a maximum moisture content.
  • Solubility: While often described as soluble in water and organic solvents, understanding its specific solubility profiles can be important for process design.

The Impact of Specifications on Application

For pharmaceutical synthesis, the purity of 2-Methyl-2-propyl-1,3-propanediol directly impacts the quality of the Active Pharmaceutical Ingredient (API) produced. For example, in the synthesis of carisoprodol, residual impurities could lead to toxic by-products or reduced therapeutic effect. In organic synthesis, a high assay ensures predictable reaction outcomes and efficient use of materials. Therefore, when you buy this compound, it is imperative to request and review the Certificate of Analysis (CoA) from the manufacturer or supplier.

Finding Reliable Suppliers for Quality Assurance

Procuring chemicals with precise specifications requires partnering with reliable B2B suppliers. Companies often search for '2-Methyl-2-propyl-1,3-propanediol supplier China' or 'buy CAS 78-26-2' to identify trusted manufacturers. A reputable supplier will not only meet the defined specifications but also provide comprehensive documentation and responsive customer support. Understanding these specifications empowers formulators and chemists to make informed purchasing decisions, ensuring the integrity and success of their chemical processes.