Essential Chemical Building Block: Understanding 2-Amino-5-bromobenzamide's Properties
In the realm of organic chemistry and pharmaceutical synthesis, specific molecules serve as indispensable building blocks, enabling the creation of complex and vital compounds. 2-Amino-5-bromobenzamide (CAS 16313-66-9) is one such key intermediate, prized for its versatile structure and reactivity. For researchers and procurement specialists looking to buy 2-amino-5-bromobenzamide, a thorough understanding of its properties is fundamental to its effective application.
Chemical Identity and Physical Characteristics
2-Amino-5-bromobenzamide is characterized by its molecular formula, C7H7BrN2O, and a molecular weight of approximately 215.05 g/mol. Its CAS number, 16313-66-9, uniquely identifies it within chemical databases. Physically, it typically presents as an off-white to light yellow solid, a common appearance for many aromatic organic compounds. Its melting point, often cited in the range of 183-185°C or 189-191°C depending on purity and source, indicates its solid state at room temperature. These physical properties are crucial for handling, storage, and formulation.
Reactivity and Applications
The significance of 2-Amino-5-bromobenzamide lies in its functional groups. The presence of an amine (-NH2) group and a primary amide (-CONH2) group on a brominated benzene ring provides multiple avenues for chemical transformation. The amine group can participate in nucleophilic substitution and condensation reactions, while the bromine atom is an excellent leaving group for cross-coupling reactions, a staple in modern synthetic organic chemistry. This makes it an ideal starting material for synthesizing diverse heterocyclic compounds and complex pharmaceutical scaffolds. As a result, it is frequently employed as a pharmaceutical intermediate and a versatile building block in organic synthesis for research and development purposes.
Handling and Storage Recommendations
When working with 2-Amino-5-bromobenzamide, as with any chemical intermediate, proper handling and storage practices are essential to maintain its integrity and ensure safety. It is typically stored in a cool, dry place, away from direct sunlight and incompatible materials. Some sources recommend storage under an inert atmosphere to prevent degradation, particularly for long-term storage. While generally considered stable, consulting the Safety Data Sheet (SDS) provided by the manufacturer or supplier is always recommended for detailed safety information, including hazard statements (e.g., H315, H319, H335) and precautionary statements.
Sourcing Considerations
For those looking to procure this compound, partnering with reputable manufacturers and suppliers is key. Ensuring the requested purity levels are met and understanding the analytical data provided (e.g., HPLC purity) are critical steps. Competitive pricing from reliable sources, especially when purchasing in bulk or for large-scale projects, is also a significant consideration. Whether for laboratory research or industrial synthesis, understanding the properties of 2-Amino-5-bromobenzamide empowers chemists to utilize it effectively and safely.
Perspectives & Insights
Chem Catalyst Pro
“2-Amino-5-bromobenzamide (CAS 16313-66-9) is one such key intermediate, prized for its versatile structure and reactivity.”
Agile Thinker 7
“For researchers and procurement specialists looking to buy 2-amino-5-bromobenzamide, a thorough understanding of its properties is fundamental to its effective application.”
Logic Spark 24
“Chemical Identity and Physical Characteristics2-Amino-5-bromobenzamide is characterized by its molecular formula, C7H7BrN2O, and a molecular weight of approximately 215.”