The vast landscape of chemical compounds offers a wealth of building blocks for innovation across industries. Among these, 2-Amino-5-nitrobenzophenone, identified by its CAS number 1775-95-7, stands out as a crucial intermediate, particularly for the pharmaceutical sector. Its specific chemical structure and reactive functional groups make it indispensable for synthesizing complex organic molecules. This article provides an overview of its properties, applications, and how procurement professionals can effectively source it.

Chemical Properties and Identification

2-Amino-5-nitrobenzophenone is characterized by its distinct chemical structure, featuring a benzophenone core with an amino group (-NH2) at the 2-position and a nitro group (-NO2) at the 5-position of one of the phenyl rings. This arrangement imparts specific reactivity, making it a versatile compound for further chemical transformations. Physically, it typically presents as a yellow to orange crystalline powder, with a high purity often specified as ≥97% Min. Its molecular formula is C13H10N2O3, and its molecular weight is approximately 242.23 g/mol. The melting point is generally reported in the range of 161-168 °C, confirming its solid state under standard conditions.

Applications as a Pharmaceutical Intermediate

The primary utility of 2-Amino-5-nitrobenzophenone lies in its role as an intermediate for Active Pharmaceutical Ingredients (APIs). Its functional groups allow for a variety of chemical reactions, including reduction of the nitro group to an amine, acylation or alkylation of the existing amino group, and participation in condensation or cyclization reactions. These transformations are fundamental in constructing the complex molecular architectures found in many modern pharmaceuticals. Therefore, a consistent and reliable supply of high-quality 2-Amino-5-nitrobenzophenone is essential for pharmaceutical manufacturers to maintain their production schedules and ensure the quality of their end products.

Sourcing and Procurement Strategies

For companies needing to buy 2-Amino-5-nitrobenzophenone, strategic sourcing is key. The global market offers numerous suppliers, with many based in China known for competitive pricing and significant production capacities. When selecting a supplier, it is important to:

  • Verify Purity: Always obtain a Certificate of Analysis (CoA) confirming the purity meets your project's requirements (e.g., ≥97% Min.).
  • Assess Supplier Reliability: Look for suppliers with a proven track record, good customer service, and the ability to provide consistent supply.
  • Compare Pricing: Request quotes from multiple manufacturers and distributors to find the best price for your required quantity. Consider bulk purchase options for cost savings.
  • Review Safety Data: Familiarize yourself with the Safety Data Sheet (SDS) for safe handling and storage procedures.

Conclusion

2-Amino-5-nitrobenzophenone (CAS 1775-95-7) is a cornerstone chemical intermediate, critical for the advancement of pharmaceutical research and manufacturing. By understanding its properties and implementing effective procurement strategies, businesses can ensure access to this vital compound, enabling them to drive innovation and maintain robust production pipelines.