For scientists and procurement specialists in the chemical and pharmaceutical industries, a thorough understanding of a compound's properties and its sourcing landscape is crucial. Ethacrynic Acid (CAS 58-54-8) is a prime example of a chemical intermediate whose utility and market dynamics warrant close examination. This article explores its key chemical attributes and provides guidance on sourcing this vital compound from leading manufacturers in China.

Ethacrynic Acid, chemically known as [2,3-dichloro-4-(2-methylenebutanoyl)phenoxy]acetic acid, possesses a unique molecular structure that underpins its pharmacological activity. As a phenoxyacetic acid derivative, it features an α,β-unsaturated ketone group, contributing to its reactivity and mechanism of action as a potent loop diuretic. Its molecular formula is C13H12Cl2O4, with a molar mass of approximately 303.14 g/mol. The compound typically appears as a white powder, indicating its solid state under standard conditions.

The primary application of Ethacrynic Acid is as a pharmaceutical intermediate, essential for synthesizing drugs used to manage edema associated with conditions like heart failure, liver cirrhosis, and kidney disease. Its effectiveness stems from its ability to inhibit the NKCC2 transporter in the thick ascending limb of the loop of Henle. Beyond its medical role, its chemical structure also makes it a subject of interest in organic synthesis research, where it can serve as a starting material or reagent for developing novel compounds. When considering to buy Ethacrynic Acid, ensuring it meets the required purity specifications for these applications is key.

For those looking to procure Ethacrynic Acid, China has become a leading source for high-quality chemical intermediates. Manufacturers in China have invested heavily in advanced synthesis technologies and robust quality management systems. This allows them to produce Ethacrynic Acid with high purity, often exceeding 98% or 99%, which is critical for pharmaceutical use. Engaging directly with a China-based manufacturer can also lead to significant cost savings, as it bypasses multiple distribution layers, resulting in a more competitive ethacrynic acid price, especially for bulk orders.

When selecting a supplier, it is advisable to request detailed technical documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS), to verify product quality and handling information. Building a relationship with a reliable manufacturer ensures not only the quality of the product but also the consistency of supply, which is vital for ongoing research and production. We pride ourselves on being a trusted source for Ethacrynic Acid, offering both exceptional product quality and responsive customer service. Contact us to learn more about our manufacturing capabilities and to obtain a quote for your procurement needs.