Understanding the fundamental chemical properties of an intermediate is crucial for its effective utilization in complex organic synthesis. Ethyl 2-BOC-aminothiazole-5-carboxylate (CAS: 302964-01-8) is a prime example of such a compound, whose specific structural features dictate its utility, particularly within the pharmaceutical industry. As a professional chemical manufacturer and supplier based in China, we are committed to providing detailed insights into the compounds we offer, enabling our clients to maximize their synthetic potential.

The molecular formula of Ethyl 2-BOC-aminothiazole-5-carboxylate is C11H16N2O4S, with a molecular weight of 272.321 g/mol. Its physical form is typically described as a light yellow to yellow powder, indicating a solid state at room temperature. The presence of the BOC (tert-butoxycarbonyl) protecting group on the amine nitrogen of the thiazole ring is a key feature. This group imparts stability to the amine, preventing its participation in unwanted reactions during synthesis, while allowing for controlled deprotection at a later stage when required. This selectivity is invaluable in multi-step synthetic pathways, common in the creation of Active Pharmaceutical Ingredients (APIs).

The thiazole ring itself is a heterocycle that is often incorporated into biologically active molecules due to its favorable pharmacological properties. In the case of Ethyl 2-BOC-aminothiazole-5-carboxylate, the ester functionality at the 5-position of the thiazole ring provides another reactive site for further chemical transformations. This dual functionality – the protected amine and the reactive ester – makes it a versatile building block for creating diverse molecular structures. When you are looking to buy this intermediate for your research or production, these inherent chemical characteristics are what make it so valuable for sophisticated syntheses.

The synthesis of Dasatinib, a crucial anti-cancer drug, heavily relies on this intermediate. The specific arrangement of functional groups in Ethyl 2-BOC-aminothiazole-5-carboxylate allows chemists to efficiently construct the complex molecular architecture of Dasatinib. The ability to source this compound with high assay (≥98.0%) from a reliable manufacturer in China ensures that the subsequent synthetic steps can proceed with predictable outcomes, minimizing impurities and maximizing yield. For any serious buyer, understanding these chemical properties translates directly into better planning and more successful outcomes in their own synthetic endeavors.

In conclusion, the chemical properties of Ethyl 2-BOC-aminothiazole-5-carboxylate, particularly the presence of the BOC protecting group and the reactive ester on a thiazole core, make it an indispensable intermediate for advanced organic synthesis. As a leading supplier, we provide this compound with the quality and specifications demanded by the pharmaceutical industry, supporting your critical research and manufacturing needs. We encourage you to inquire about purchasing this essential chemical from our production facilities.