Ethyl 4-Chlorobutanoate: Key Intermediate for Pharmaceutical Synthesis
The pharmaceutical industry constantly seeks high-purity chemical intermediates to develop and manufacture life-saving drugs. Ethyl 4-Chlorobutanoate (CAS: 3153-36-4) is one such compound, playing a pivotal role as a building block in the synthesis of various Active Pharmaceutical Ingredients (APIs) and their precursors. Its specific chemical structure and reactivity make it an invaluable asset for pharmaceutical researchers and manufacturers worldwide.
With a chemical name of ethyl 4-chlorobutanoate, this compound is a clear yellow to brownish liquid, distinguished by its high purity (≥98.0%) and low moisture content (≤0.2%). These specifications are critical for pharmaceutical applications, where even minor impurities can affect the efficacy and safety of the final drug product. The low melting point (-70°C) and moderate boiling point (186°C) of Ethyl 4-Chlorobutanoate ensure its stability and ease of handling in various reaction environments commonly found in pharmaceutical R&D and production facilities.
The significance of Ethyl 4-Chlorobutanoate in pharmaceutical synthesis stems from its versatility as an intermediate. It is instrumental in the creation of complex molecular structures, particularly those requiring specific functional group arrangements. For instance, it is a key precursor in the synthesis of certain cyclopropane derivatives, a structural motif found in numerous therapeutic agents. Additionally, its utility extends to the preparation of other vital intermediates, such as 4-iodobutyric acid ethyl ester, further expanding its application scope within the pharmaceutical value chain. Sourcing this compound from a trusted manufacturer ensures that these synthesis pathways are robust and efficient.
When pharmaceutical companies look to buy Ethyl 4-Chlorobutanoate, they prioritize suppliers who guarantee consistent quality and reliable delivery. Manufacturers in China, known for their advanced chemical production capabilities, are often preferred sources. These suppliers offer a competitive edge by providing high-purity Ethyl 4-Chlorobutanoate at attractive prices, coupled with comprehensive technical documentation like CoAs and MSDSs. For procurement managers, securing a partnership with an established Ethyl 4-Chlorobutanoate supplier in China means ensuring an uninterrupted supply of this critical material for their production pipelines.
The role of Ethyl 4-Chlorobutanoate in bridging basic research to large-scale pharmaceutical manufacturing cannot be overstated. Its well-defined chemical properties and established synthesis routes make it an accessible and efficient intermediate. Whether for early-stage drug discovery or commercial production, having access to high-quality Ethyl 4-Chlorobutanoate is essential. As a dedicated provider of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the pharmaceutical sector with premium-grade Ethyl 4-Chlorobutanoate and related custom synthesis services. We understand the demands of pharmaceutical manufacturing and strive to be a reliable partner for your critical intermediate needs.
Perspectives & Insights
Logic Thinker AI
“Its specific chemical structure and reactivity make it an invaluable asset for pharmaceutical researchers and manufacturers worldwide.”
Molecule Spark 2025
“With a chemical name of ethyl 4-chlorobutanoate, this compound is a clear yellow to brownish liquid, distinguished by its high purity (≥98.”
Alpha Pioneer 01
“These specifications are critical for pharmaceutical applications, where even minor impurities can affect the efficacy and safety of the final drug product.”