Organic synthesis is the cornerstone of modern chemistry, enabling the creation of novel molecules with diverse applications, from life-saving pharmaceuticals to advanced materials. Within this field, specific building blocks are indispensable for their reactivity and versatility. Ethyl 8-Bromooctanoate (CAS 29823-21-0) stands out as one such critical reagent, valued by research scientists for its functional group and chain length.

As a bifunctional molecule, Ethyl 8-Bromooctanoate possesses both an ester group and a terminal bromide. The ester functionality can undergo various transformations common to carboxylic acid derivatives, such as hydrolysis to the corresponding acid or reduction to an alcohol. More significantly, the primary alkyl bromide serves as an excellent leaving group, making it highly reactive in nucleophilic substitution reactions (SN2). This dual reactivity allows for the introduction of an eight-carbon chain with differentiated functional handles into larger molecular architectures.

Scientists looking to buy Ethyl 8-Bromooctanoate for their synthesis projects often search for its CAS number, 29823-21-0, to ensure they are acquiring the correct compound. Common reactions involving this reagent include:

  • Alkylation: Reacting with various nucleophiles, such as amines, thiols, alkoxides, or stabilized carbanions, to form new carbon-heteroatom or carbon-carbon bonds. This is a fundamental step in constructing complex organic molecules.
  • Grignard Reagent Formation: Conversion to the corresponding Grignard reagent, which can then react with carbonyl compounds (aldehydes, ketones, esters) to form alcohols or ketones.
  • Further Functionalization: The ester group itself can be modified. For instance, hydrolysis yields 8-bromooctanoic acid, which can then be activated for amide bond formation or further esterification.

The reliable supply of high-quality Ethyl 8-Bromooctanoate is crucial for researchers. When seeking to purchase this compound, it is advisable to partner with established suppliers and manufacturers who can guarantee purity and consistency. Information on price and availability is readily accessible from chemical distributors. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing such essential reagents, ensuring that research projects have access to the materials they need for successful outcomes.

For those involved in drug discovery or custom synthesis, Ethyl 8-Bromooctanoate offers a convenient way to introduce an eight-carbon linker with a reactive endpoint. Its predictable reactivity and availability make it a go-to choice for chemists aiming to build complex molecular frameworks efficiently. Ensuring a steady supply from a trusted manufacturer is key to maintaining research momentum.