The pharmaceutical industry's relentless pursuit of novel therapeutics necessitates a steady supply of high-quality intermediates. (R)-1-(tert-Butoxycarbonyl)-3-Hydroxypyrrolidine (CAS: 109431-87-0), also known as (R)-1-Boc-3-hydroxypyrrolidine, has gained prominence as a critical component in the synthesis of advanced pharmaceuticals, most notably as an Evocalcet intermediate. Evocalcet, an agonist for the calcium-sensing receptor, plays a role in managing parathyroid hormone secretion, highlighting the importance of this chiral building block in medical advancements.

For pharmaceutical companies and research institutions, sourcing this specific intermediate requires identifying trustworthy manufacturers and suppliers, especially within major chemical production regions like China. Procurement managers often initiate their search with targeted queries such as 'Evocalcet intermediate manufacturer' or 'buy (R)-1-Boc-3-hydroxypyrrolidine China'. The ability to secure a reliable supply of this compound, with a typical purity of 98% or higher, is essential for scaling up production and ensuring batch-to-batch consistency.

The chemical and physical characteristics of (R)-1-Boc-3-hydroxypyrrolidine, such as its appearance as a white to off-white powder and its stability under controlled conditions, make it a practical choice for synthetic chemists. Its application extends beyond Evocalcet to the development of other complex molecules, including ligands for nicotinic acetylcholine receptors, making it a versatile tool in medicinal chemistry.

When selecting a supplier for this vital intermediate, factors such as offering a free sample, providing a detailed Certificate of Analysis (CoA), and ensuring competitive pricing are key considerations. Companies that actively search for 'CAS 109431-87-0 price quote' often aim to balance cost-efficiency with unwavering quality. Establishing a relationship with a manufacturer that offers robust supply chain management and potentially custom synthesis services can be highly advantageous.

The global demand for advanced pharmaceutical intermediates like (R)-1-Boc-3-hydroxypyrrolidine underscores the importance of a well-developed chemical supply network. By partnering with leading Chinese manufacturers and suppliers, pharmaceutical developers can ensure they have access to this essential chiral synthon, thereby facilitating the timely progression of their drug discovery and development programs. Secure your supply of this crucial Evocalcet intermediate by connecting with trusted industry partners.