For professionals in the chemical and pharmaceutical sectors, the selection of high-quality building blocks is fundamental to successful product development. 1,1,1-Trifluoro-2-propanol (CAS 374-01-6) has emerged as a vital component in modern organic synthesis, prized for its unique fluorinated structure and versatile chemical reactivity. Understanding its properties and how to procure it effectively from a leading manufacturer is essential for any research scientist or procurement manager.

Chemical Profile and Properties

1,1,1-Trifluoro-2-propanol is a clear, colorless liquid characterized by its distinctive trifluoromethyl group. With a molecular formula of C3H5F3O and a molecular weight of approximately 114.07 g/mol, it exhibits a density of 1.259 g/mL and a boiling point of 81-82 °C. These physical attributes, combined with its chemical nature, make it an excellent choice for various synthesis applications. It readily dissolves in water and common organic solvents, enhancing its usability in diverse reaction conditions.

The Significance of 1,1,1-Trifluoro-2-propanol as a Building Block

As a chemical building block, 1,1,1-Trifluoro-2-propanol offers researchers the ability to introduce a trifluoromethyl moiety into larger molecules. This functional group is known to impart desirable characteristics such as:

  • Increased Lipophilicity: Beneficial for drug penetration and absorption.
  • Enhanced Metabolic Stability: Helps in prolonging the efficacy of pharmaceuticals and agrochemicals.
  • Modified Acidity/Basicity: Allows for fine-tuning of molecular properties.
  • Improved Thermal Stability: Useful in material science applications.

These properties make it a sought-after intermediate in the synthesis of complex organic molecules, including APIs for pharmaceuticals and active ingredients for pesticides. Procurement specialists often source this compound to meet the demands of stringent R&D pipelines.

Choosing a Reliable Manufacturer and Supplier

When considering the purchase of 1,1,1-Trifluoro-2-propanol, partnering with a reputable manufacturer, particularly one based in China, can provide a strategic advantage. A good supplier ensures product purity, consistent quality, and reliable availability, crucial factors for uninterrupted research and production. It is advisable to request a quotation from potential suppliers, comparing not only the price but also their quality control measures and delivery capabilities.

For organizations looking to buy 1,1,1-Trifluoro-2-propanol, our company stands as a dedicated manufacturer and supplier. We are committed to providing high-grade chemical intermediates that meet the rigorous standards of the global chemical industry. We encourage you to contact us to obtain a quote and discuss your specific requirements for this essential fluorinated building block.