The pharmaceutical industry relies heavily on the precision and reliability of its raw material sourcing. For the synthesis of critical antibiotics like ciprofloxacin, the intermediate 7-Chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic Acid is indispensable. This article delves into the essential aspects for procurement managers and R&D scientists looking to source this vital chemical, often referred to as fluoroquinolonic acid, from reputable manufacturers.

Chemical Profile and Key Applications

7-Chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic Acid (CAS: 86393-33-1) is characterized by its molecular formula C13H9ClFNO3 and a molecular weight of 281.67 g/mol. Typically appearing as a yellow or light yellow powder, its chemical properties are finely tuned for its primary application: serving as a key intermediate in the manufacturing of ciprofloxacin. This intermediate's structural integrity and purity directly influence the efficacy and safety of the final drug. Beyond ciprofloxacin, its chemical scaffold also makes it a subject of interest for developing next-generation fluoroquinolone antibiotics, underscoring its ongoing importance in pharmaceutical research.

Specifications and Quality Assurance for Buyers

When evaluating suppliers for 7-Chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic Acid, specific quality parameters are non-negotiable. A high assay, such as ≥99.0% by HPLC, is critical for ensuring efficient downstream synthesis. Furthermore, strict control over impurities, including limits on unknown single impurities (≤0.5%) and total impurities (≤1.0%), along with low loss on drying (≤0.5%), are indicative of a high-quality product that meets pharmaceutical industry standards. Buyers should always request a comprehensive Certificate of Analysis (CoA) from their chosen manufacturer.

Choosing a Reliable Manufacturer and Supplier

The global pharmaceutical supply chain often looks to specialized chemical manufacturers for intermediates like fluoroquinolonic acid. Sourcing from a manufacturer in China can offer significant advantages in terms of cost-effectiveness and production capacity. However, it is crucial to partner with a supplier that demonstrates a strong commitment to quality control, regulatory compliance, and consistent production. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing high-grade pharmaceutical intermediates, ensuring that clients receive products that meet rigorous international standards. When you decide to purchase this intermediate, prioritize suppliers who offer transparency regarding their manufacturing processes and quality assurance measures.

Market Trends and Procurement Strategies

The demand for effective antibacterial agents remains high, driving the consistent need for intermediates like fluoroquinolonic acid. Procurement managers should establish long-term relationships with trusted suppliers to ensure a stable supply and competitive pricing. Understanding the market price of fluoroquinolonic acid and exploring bulk purchase options can lead to significant cost savings. Ultimately, securing a dependable source for this critical intermediate is key to maintaining robust production lines and supporting the development of vital pharmaceutical products.