In the realm of chemical synthesis, the selection of appropriate reagents and intermediates directly impacts the efficiency, yield, and overall success of a project. 1,4-Dibromo-2-iodobenzene (CAS: 89284-52-6) is a prime example of such a crucial compound, valued for its versatile reactivity and its role as a building block in pharmaceuticals, agrochemicals, and advanced materials. For procurement specialists and synthetic chemists, understanding how to expertly source this intermediate is key to optimizing production and research efforts.

The Chemical Significance of 1,4-Dibromo-2-iodobenzene

This tri-halogenated aromatic compound, C6H3Br2I, offers a unique advantage due to the differential reactivity of its halogen substituents. The carbon-iodine bond is typically more labile than the carbon-bromine bonds in various cross-coupling reactions, such as palladium-catalyzed Suzuki, Heck, or Sonogashira couplings. This characteristic allows for regioselective, stepwise functionalization of the benzene ring, enabling the precise construction of complex molecular architectures. Such control is indispensable for creating molecules with specific pharmacological activities, desired material properties, or targeted biological functions.

Applications Across Key Industries

The demand for 1,4-Dibromo-2-iodobenzene is strong across several sectors:

  • Pharmaceuticals: As a key intermediate in API synthesis, it facilitates the creation of complex drug molecules with intricate structures, essential for treating various diseases.
  • Agrochemicals: It's used to build novel herbicides, insecticides, and fungicides that offer improved efficacy and safety profiles.
  • Materials Science: The compound is utilized in the synthesis of organic semiconductors, conductive polymers, and liquid crystals for next-generation electronic devices and displays.
  • Research & Development: Its versatility makes it a staple in academic and industrial labs exploring new synthetic methodologies and creating novel compounds for screening.

Expert Guidance for Sourcing 1,4-Dibromo-2-iodobenzene

To ensure a successful procurement of 1,4-Dibromo-2-iodobenzene (CAS: 89284-52-6), consider these expert tips:

  • Prioritize Purity: For demanding applications like pharmaceutical synthesis, a purity of 99% is often preferred. Always request and verify the Certificate of Analysis (CoA) from the supplier.
  • Choose Reputable Manufacturers: Partner with established chemical manufacturers and suppliers, particularly those with a strong presence in China, known for their competitive pricing and production capabilities.
  • Request Quotes for Bulk Orders: Obtaining quotes from multiple suppliers for your required quantities (e.g., grams for R&D, kilograms for pilot scale) is crucial for price negotiation and budget planning.
  • Evaluate Lead Times and Delivery: Understand the supplier's production capacity and delivery schedules to ensure they align with your project timelines. Efficient logistics are as important as product quality.
  • Utilize Sample Programs: Many reputable manufacturers offer free samples, allowing you to test the quality and suitability of the intermediate before committing to a large purchase.

By employing a strategic sourcing approach, chemical professionals can secure a reliable supply of high-quality 1,4-Dibromo-2-iodobenzene (CAS: 89284-52-6), thereby enhancing their synthetic capabilities and driving innovation. If you are looking to buy this essential intermediate, we invite you to contact us. We are a leading supplier committed to providing high-purity chemicals and exceptional service to support your research and manufacturing needs. Get a quote and sample today.