The creation of complex organic molecules, especially those destined for pharmaceutical applications, relies on the precise synthesis of key intermediates. 4-(5-Bromo-2-chlorobenzyl)phenol (CAS 864070-18-8) stands out as a critical compound in this regard, valued for its specific chemical structure and the versatility it offers in synthetic organic chemistry. This article explores the synthetic pathways, chemical properties, and the role of this intermediate from the perspective of an experienced chemical manufacturer.

Understanding the Synthesis of 4-(5-Bromo-2-chlorobenzyl)phenol

The synthesis of 4-(5-Bromo-2-chlorobenzyl)phenol typically involves a reaction that carefully couples a substituted benzyl alcohol with a phenol derivative. A common route mentioned in chemical literature is the reaction between 5-bromo-2-chlorobenzyl alcohol and phenol under acidic catalysis. This process requires meticulous control over reaction temperature, catalyst concentration, and reaction time to achieve high yields and the desired product purity. The subsequent purification steps are equally crucial to remove any unreacted starting materials or byproducts, ensuring the final product meets stringent specifications, often exceeding 99% purity. When businesses look to buy 4-(5-bromo-2-chlorobenzyl)phenol, they seek manufacturers with demonstrated expertise in such precise synthesis.

Chemical Properties and Reactivity Profile

As a white crystalline solid, 4-(5-Bromo-2-chlorobenzyl)phenol possesses a defined melting point, typically in the range of 70-72°C, and a relatively high boiling point. Its molecular formula, C13H10BrClO, highlights the presence of halogen substituents and a phenolic hydroxyl group, both of which are key functional groups for further chemical transformations. The bromine and chlorine atoms offer sites for nucleophilic substitution or cross-coupling reactions, while the phenol group can undergo esterification, etherification, or electrophilic aromatic substitution. This rich reactivity profile makes it a versatile intermediate for creating a wide array of downstream products, particularly within the pharmaceutical sector.

The Importance of a Reliable Manufacturer and Supplier

For companies engaged in pharmaceutical R&D and manufacturing, securing a consistent supply of high-quality intermediates is non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD., as a prominent pharmaceutical intermediate supplier in China, specializes in providing compounds like 4-(5-Bromo-2-chlorobenzyl)phenol. Our manufacturing processes are optimized for purity and yield, supported by robust quality assurance systems. We understand the market demand for reliable sourcing and competitive 4-[(5-bromo-2-chlorophenyl)methyl]phenol price points.

Role in Pharmaceutical Innovation

The significance of 4-(5-Bromo-2-chlorobenzyl)phenol extends to its role in the synthesis of active pharmaceutical ingredients (APIs) for critical medications, such as those used in diabetes management. Its availability as a high-purity intermediate directly supports the pharmaceutical industry's innovation pipeline, enabling the development and scale-up of new drug candidates. When sourcing CAS 864070-18-8, partnering with an experienced chemical synthesis expert ensures not only product quality but also adherence to the demanding standards of the pharmaceutical sector.

Our commitment as a manufacturer and supplier is to provide the essential chemical tools that empower scientific advancement. By focusing on precision synthesis and consistent quality, we aim to be your trusted partner for critical intermediates like 4-(5-Bromo-2-chlorobenzyl)phenol.