In the realm of fine chemicals and pharmaceutical intermediates, a thorough understanding of each compound's characteristics is crucial for researchers and procurement specialists alike. This article delves into 2-Phenoxyethylamine (CAS: 1758-46-9), exploring its fundamental properties, common synthesis pathways, and guidance on identifying dependable suppliers for your purchase. As a key intermediate, its availability and quality directly impact the success of numerous downstream applications.

Chemical and Physical Properties Demystified
2-Phenoxyethylamine, with the molecular formula C8H11NO, presents as a clear, colorless to light yellow liquid. Its purity is a critical factor, typically specified at ≥98.0% to ensure its efficacy in sensitive applications. Key physical data, such as a density of 1.048 g/mL at 25°C and a boiling point of 101-103°C at 4 mm Hg, provide essential parameters for handling and processing. Its refractive index (n20/D 1.536) and flash point (225°F) are also important considerations for safety and industrial use. When considering a purchase, always verify these specifications with the manufacturer.

Common Synthesis Routes and Considerations
While detailed proprietary synthesis methods vary among manufacturers, 2-Phenoxyethylamine is often prepared through reactions involving phenol and a suitable ethylamine precursor. One common approach might involve the reaction of phenol with 2-chloroethylamine or a related derivative under basic conditions to facilitate the ether linkage. Another pathway could involve the reduction of a phenoxyacetonitrile or phenoxyacetamide derivative. Understanding these general synthetic principles can help in evaluating the robustness of a manufacturer's production process and the potential impurity profiles of the final product. For procurement managers, ensuring the manufacturer has optimized their synthesis for high yield and purity is a key consideration.

Finding Reliable Suppliers for Your Needs
Sourcing 2-Phenoxyethylamine reliably requires diligence in selecting suppliers. For businesses looking to buy, it's advisable to partner with manufacturers who can demonstrate consistent quality, adherence to specifications (like ≥98.0% purity), and a stable supply chain. Companies located in major chemical production hubs, such as China, often offer competitive pricing without compromising on quality, provided thorough vetting is conducted. When inquiring about price and availability, clearly state the CAS number (1758-46-9) and your expected order volume. Requesting samples for in-house quality control before committing to a large purchase is also a recommended practice.

Applications Driving the Market
The primary applications of 2-Phenoxyethylamine lie in its role as an intermediate for organic synthesis and the pharmaceutical industry. Its structural features make it suitable for the development of compounds with potential pharmacological activities, including beta-blocking and vasodilating properties. It also finds use as an inhibitor of beta-glucosidase, relevant in biochemical research. As the demand for novel pharmaceuticals and complex organic molecules continues to grow, the importance of readily available, high-quality 2-Phenoxyethylamine will only increase.

In summary, a comprehensive understanding of 2-Phenoxyethylamine's properties, alongside a strategic approach to supplier selection, is essential for any organization relying on this critical chemical. By focusing on reputable manufacturers and clear communication, procurement professionals can secure a consistent supply of this valuable intermediate.