In the complex world of chemical synthesis, certain molecules stand out for their versatility and wide-ranging applications. 4-Piperidinemethanol, with its CAS number 6457-49-4, is one such compound, serving as a critical intermediate across various sectors, most notably in pharmaceuticals and advanced organic chemistry research. Its unique structural characteristics allow for diverse chemical transformations, making it a sought-after building block for creating more complex molecules. This article explores its key chemical applications and offers insights for those looking to purchase this valuable compound.

Understanding the Chemical Structure and Properties

4-Piperidinemethanol, chemically known as piperidin-4-ylmethanol, possesses the molecular formula C6H13NO. Its structure combines a saturated heterocyclic amine (piperidine) with a primary alcohol functional group (-CH2OH). This duality in functional groups—an amine and an alcohol—is the source of its broad reactivity. Typically appearing as a white crystalline powder, it has a purity level often exceeding 97%, which is essential for precise chemical synthesis. Important physical properties include a melting point in the range of 55-59 °C and a boiling point of 118-120 °C at 10 mmHg, making it manageable under standard laboratory and industrial conditions. Its solubility in water further expands its utility in aqueous reaction systems.

Core Applications in Pharmaceutical Synthesis

The most prominent application of 4-Piperidinemethanol lies in the pharmaceutical industry. It serves as a crucial intermediate in the synthesis of numerous Active Pharmaceutical Ingredients (APIs). The piperidine ring is a common scaffold found in many drugs, and the hydroxymethyl group provides a convenient attachment point for further functionalization or for building more elaborate molecular structures. For example, it can be used to introduce specific side chains or to create chiral centers, which are vital for drug efficacy and specificity. Researchers and pharmaceutical companies seeking to buy 4-Piperidinemethanol often do so for its established role in producing a wide array of therapeutic agents, including antipsychotics, analgesics, and cardiovascular drugs.

Role in Research and Development (R&D)

Beyond large-scale pharmaceutical manufacturing, 4-Piperidinemethanol is an indispensable tool for organic chemists in research and development settings. Its bifunctional nature allows for a variety of chemical reactions, including alkylation, acylation, and oxidation. This makes it a valuable starting material for:

  • Drug Discovery: Synthesizing novel compound libraries for screening against new therapeutic targets.
  • Method Development: Testing new synthetic methodologies or catalytic systems.
  • Academic Research: Exploring new heterocyclic compounds with potential biological activity or unique material properties.

Researchers often depend on reliable suppliers that can provide small to medium quantities for experimental purposes. The ability to easily purchase this chemical with guaranteed purity is essential for reproducible research outcomes.

Custom Synthesis and Specialty Chemicals

The versatility of 4-Piperidinemethanol also makes it a popular choice for custom synthesis projects. Chemical companies that offer bespoke synthesis services can utilize this intermediate to create highly specialized molecules tailored to client specifications. Whether it's a specific derivative for a new material or a unique scaffold for an investigational drug, 4-Piperidinemethanol provides a solid foundation. For companies requiring these services, engaging with a competent manufacturer that can provide a detailed quote is a critical first step.

Procurement: Quality, Price, and Partnership

When you are ready to purchase 4-Piperidinemethanol, it is crucial to identify a reputable manufacturer or supplier. While competitive price is always a consideration, it should not overshadow the importance of quality and reliability. A supplier that offers consistent purity, robust documentation (such as a Certificate of Analysis), and stable supply chain management is invaluable. Furthermore, building a relationship with a supplier who can offer technical support and responsive customer service ensures a smooth procurement process. Many buyers find that sourcing from established China manufacturers offers a good balance of cost-effectiveness and quality.

In summary, 4-Piperidinemethanol (CAS 6457-49-4) is a highly versatile chemical intermediate with significant applications in pharmaceutical synthesis, R&D, and custom manufacturing. Its well-defined chemical properties and reactivity make it a cornerstone compound for chemical innovation.