In the realm of organic chemistry, understanding the specific attributes of chemical compounds is key to unlocking their full potential in synthesis and research. 2-Bromo-6-fluorotoluene, identified by its CAS number 1422-54-4, is a compound that offers a unique combination of reactivity and stability, making it a valuable asset for chemists worldwide. This article explores its distinctive physical and chemical properties and elucidates its diverse applications.

Physical Characteristics for Practical Use

As a liquid, 2-Bromo-6-fluorotoluene typically presents as colorless to yellow, a visual indicator of its purity. Its density, measured at 1.53 g/cm³, suggests a relatively compact molecular structure. The compound's boiling point, recorded at 75-76°C at 10 mmHg, indicates its behavior under reduced pressure, while its flash point of 76°C provides crucial information regarding its flammability, guiding safe handling practices. Furthermore, its refractive index of 1.535 and a vapor pressure of 0.00166 mmHg at 25°C offer deeper insights into how it interacts with light and its volatility, respectively. These well-defined physical parameters are critical for ensuring precision in chemical processes where this compound is used.

Chemical Reactivity and Functional Utility

The chemical significance of 2-Bromo-6-fluorotoluene lies in its functional groups. The presence of both a bromine atom and a fluorine atom on the toluene backbone makes it highly reactive, particularly in substitution reactions. This dual halogenation allows for targeted chemical transformations, making it an excellent organic intermediate. Chemists can leverage these reactive sites to introduce specific functionalities or to build more complex molecules for various applications, including the synthesis of pharmaceuticals and other fine chemicals. Its role as a building block is central to many synthetic strategies.

Key Applications in Chemical Synthesis

The primary utility of 2-Bromo-6-fluorotoluene is as a precursor in organic synthesis. It serves as a critical component in the development of a wide array of organic compounds. In the pharmaceutical sector, it is recognized as an important pharmaceutical intermediate, contributing to the synthesis of APIs. Its high purity (≥98%) and low water content (≤0.5%) are essential for meeting the stringent requirements of drug development and manufacturing. Researchers and industrial chemists find great value in its predictable reactivity, enabling efficient and successful synthesis pathways.

Safe Handling and Sourcing Considerations

Due to its toxic nature (UN Number 2811, Hazard Class 6.1), proper handling and storage of 2-Bromo-6-fluorotoluene are imperative. It should be stored in a cool, dry, and well-ventilated area, with containers kept tightly closed. For those looking to buy 2-Bromo-6-fluorotoluene, sourcing from reputable suppliers is crucial. Companies that provide detailed specifications, adhere to safety standards, and offer consistent product quality are preferred. Reliable 2-Bromo-6-fluorotoluene suppliers ensure that these critical intermediates are available for advanced chemical research and industrial production.

In summary, the detailed chemical properties and versatile applications of 2-Bromo-6-fluorotoluene solidify its position as an indispensable compound in the toolkit of modern synthetic chemists.