In the realm of organic chemistry, certain molecules serve as foundational elements for a multitude of advanced applications. 2-Phenylpyridine, identified by its CAS number 1008-89-5, is one such compound. Characterized by its unique structure and versatile reactivity, it plays a crucial role in sectors ranging from pharmaceuticals to cutting-edge electronic materials. Understanding its chemical properties and applications is essential for researchers and procurement professionals seeking to leverage its potential.

Chemical Profile of 2-Phenylpyridine

2-Phenylpyridine is an aromatic heterocyclic compound with the molecular formula C11H9N and a molecular weight of approximately 155.2 g/mol. It is typically supplied as a clear, colorless to yellow liquid. Key chemical properties include:

  • Structure: It consists of a pyridine ring substituted at the 2-position with a phenyl group. This arrangement provides sites for various electrophilic and nucleophilic reactions, as well as coordination chemistry due to the nitrogen atom in the pyridine ring.
  • Reactivity: The compound is amenable to functionalization on both the phenyl and pyridine rings. Common reactions include halogenation, nitration, and metal-catalyzed cross-coupling reactions, such as Suzuki and Heck couplings, which are vital for building larger, more complex molecules.
  • Physical Properties: With a boiling point around 270°C, it is a relatively stable liquid under standard conditions. Its purity, often specified as 97% or higher, is critical for its effective use in demanding applications.

Industrial Applications and Demand

The versatility of 2-Phenylpyridine translates into a significant demand across several key industries:

  1. Pharmaceutical Industry: As a vital pharmaceutical intermediate, 2-Phenylpyridine is employed in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs). Its structural features can be integrated into molecules designed to target specific biological pathways. Companies in drug development frequently look to buy such intermediates to accelerate their R&D processes.
  2. OLED Technology: In the field of organic electronics, derivatives of 2-Phenylpyridine are utilized as emissive layers or host materials in Organic Light-Emitting Diodes (OLEDs). These materials are crucial for creating energy-efficient, vibrant displays and lighting solutions. The demand for high-purity precursors for OLED synthesis is a growing market.
  3. Organic Synthesis and Catalysis: Researchers and synthetic chemists utilize 2-Phenylpyridine as a valuable building block for creating novel organic compounds. Furthermore, its ability to act as a ligand in transition metal catalysis is instrumental in developing more efficient and selective chemical transformations.

Sourcing High-Quality 2-Phenylpyridine

For businesses looking to purchase 2-Phenylpyridine (CAS 1008-89-5), it is essential to source from reliable manufacturers who can guarantee high purity and consistent quality. Factors to consider include:

  • Manufacturer Reputation: Choose established suppliers with a strong commitment to quality control and a proven track record.
  • Product Specifications: Always verify the purity level and confirm that it meets your application's requirements. Obtaining a Certificate of Analysis (CoA) is standard.
  • Pricing and Availability: Competitive pricing and reliable availability are crucial for managing project budgets and timelines. Inquire about bulk purchase options from manufacturers.
  • Customer Support: Good communication and technical support from the supplier can greatly assist in utilizing the product effectively.

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