The world of chemistry is built upon a foundation of understanding molecular properties and their consequent applications. Among the myriad of chemical compounds, intermediates like 5-Bromo-6-methoxypyridin-3-amine (CAS: 53242-18-5) are crucial for advancing scientific and industrial endeavors. This article aims to provide a comprehensive overview of this compound, detailing its key characteristics, exploring its diverse applications, and highlighting the importance of procuring it from reliable sources.

5-Bromo-6-methoxypyridin-3-amine is a heterocyclic organic compound characterized by its pyridine ring, which is substituted with three distinct functional groups: a bromine atom at the 5-position, a methoxy group at the 6-position, and an amine group at the 3-position. This specific arrangement imparts a unique reactivity profile, making it a valuable intermediate in various chemical synthesis processes. Its molecular formula is C6H7BrN2O, with a molecular weight of 203.03700. The compound is typically observed as a brown solid, a characteristic that aids in its identification and handling.

Delving into its physical and chemical properties, 5-Bromo-6-methoxypyridin-3-amine exhibits a density of 1.622 g/cm³, indicating a relatively compact molecular structure. Its boiling point is recorded at 292.4°C, suggesting good thermal stability, a desirable trait for compounds used in reactions that may involve elevated temperatures. The flash point of 130.7°C also provides important safety information for handling and storage. Furthermore, its refractive index of 1.602 is a specific physical property that can be used for identification and quality assessment. Crucially for its industrial use, it is often available with a purity of ≥98.0% as determined by HPLC, ensuring consistent and reliable performance in synthesis.

The primary utility of 5-Bromo-6-methoxypyridin-3-amine lies in its role as an intermediate in organic synthesis. The presence of the amine group allows for modifications like acylation or alkylation, while the bromine atom is an excellent leaving group for cross-coupling reactions, a cornerstone of modern synthetic chemistry. This allows chemists to build more complex molecular structures, essential for the development of pharmaceuticals, agrochemicals, and other fine chemicals. For example, it can serve as a scaffold for creating novel drug candidates targeting various diseases, or it can be incorporated into compounds designed to protect crops from pests and environmental challenges.

For researchers and procurement specialists, understanding where to buy 5-Bromo-6-methoxypyridin-3-amine is vital. Sourcing from reputable manufacturers, particularly those in China, ensures access to high-quality material at competitive prices. Companies that specialize in producing such intermediates often have robust quality control systems in place, guaranteeing the purity and consistency required for demanding applications. Whether you are looking for a supplier for R&D purposes or for large-scale production, exploring options from established chemical manufacturers is a sound strategy.

In essence, 5-Bromo-6-methoxypyridin-3-amine is a versatile and essential compound in the chemical synthesis landscape. Its well-defined properties and broad applicability make it a valuable asset for innovation in various industries. By understanding its characteristics and ensuring quality sourcing, chemists and manufacturers can effectively leverage this intermediate to achieve their synthesis goals.