Exploring Ethyl Trifluoroacetate: Properties, Applications, and Sourcing in China
Ethyl Trifluoroacetate (CAS No. 383-63-1) stands out as a remarkable compound in organic chemistry, serving as a crucial intermediate for various sophisticated syntheses, most notably in the pharmaceutical sector for the production of Celecoxib. Its classification as a colorless, transparent liquid with a molecular formula C4H5F3O2 and a molecular weight of 142.077 hints at its precise chemical nature. With a density of 1.2±0.1 g/cm³, it exhibits unique physical characteristics that are vital for its handling and application in industrial settings. As a leading ethyl trifluoroacetate supplier in China, we ensure that this compound meets the highest standards of quality and purity.
The physical and chemical properties of Ethyl Trifluoroacetate are key to its utility. Its boiling point of 61.5±3.0 °C at 760 mmHg and a melting point of -78 °C ensure it remains liquid under most standard operational temperatures, facilitating its use in diverse reaction conditions. The flash point of -1.1±0.0 °C necessitates careful handling due to its flammability, a standard consideration for many organic reagents. The high purity, indicated by an assay of ≥98.0% via gas chromatography (GC), is paramount for its application in sensitive pharmaceutical processes, a commitment that NINGBO INNO PHARMCHEM CO.,LTD. upholds diligently.
The application spectrum of Ethyl Trifluoroacetate is notably broad, with its role as an intermediate in Celecoxib (CAS 169590-42-5) synthesis being particularly significant. Celecoxib, a well-regarded NSAID, requires high-purity intermediates to meet stringent medical standards. Ethyl Trifluoroacetate's ability to introduce fluorine atoms and the trifluoroacetyl group enhances the bioactivity and stability of the resulting pharmaceutical compounds. This makes it an essential component for drug design and development. Manufacturers looking to buy ethyl trifluoroacetate for such critical processes find value in sourcing from experienced chemical manufacturers in China.
China has emerged as a global powerhouse in chemical manufacturing, and the production of Ethyl Trifluoroacetate is a testament to this. Leveraging advanced technologies, Chinese manufacturers ensure the high purity levels required for pharmaceutical and agrochemical applications. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of this industry, offering competitive pricing and reliable supply chains. Our capacity to package the product in standard 200 kg drums or offer customized packaging ensures we cater to a wide array of client needs, from research laboratories to large-scale industrial operations.
In organic synthesis, Ethyl Trifluoroacetate is valued for its versatility in introducing trifluoromethyl groups, which can significantly alter a compound's lipophilicity and metabolic stability. These attributes are highly desirable in modern drug discovery. For companies seeking a dependable source of this vital chemical, partnering with a reputable ethyl trifluoroacetate producer in China like NINGBO INNO PHARMCHEM CO.,LTD. provides access to high-quality materials, competitive pricing, and exceptional customer service, ensuring seamless integration into your production workflows.
Perspectives & Insights
Nano Explorer 01
“Ethyl Trifluoroacetate's ability to introduce fluorine atoms and the trifluoroacetyl group enhances the bioactivity and stability of the resulting pharmaceutical compounds.”
Data Catalyst One
“Manufacturers looking to buy ethyl trifluoroacetate for such critical processes find value in sourcing from experienced chemical manufacturers in China.”
Chem Thinker Labs
“China has emerged as a global powerhouse in chemical manufacturing, and the production of Ethyl Trifluoroacetate is a testament to this.”