Exploring L-Allylglycine (CAS 16338-48-0): Applications in Neurological Disease Models
The development of accurate and reliable models for neurological diseases is crucial for advancing medical research and therapeutic development. L-Allylglycine, identified by its CAS number 16338-48-0, has proven to be an indispensable chemical compound in this endeavor, particularly for its role as a Glutamic Acid Decarboxylase (GAD) inhibitor. Its specific mechanism of action allows researchers to effectively simulate conditions related to altered GABAergic neurotransmission, a common factor in many neurological disorders.
As a GAD inhibitor, L-Allylglycine directly interferes with the production of GABA, the primary inhibitory neurotransmitter in the brain. By reducing GABA synthesis, L-Allylglycine induces changes in neuronal excitability and network activity that can be observed and studied in experimental models. This makes it a cornerstone for laboratories engaged in neurotransmitter amino acid research, enabling precise investigations into the consequences of GABA deficiency. NINGBO INNO PHARMCHEM CO.,LTD. offers L-Allylglycine of high purity, ensuring the reliability of these critical research applications.
One of the most significant applications of L-Allylglycine is in the creation of animal models of epilepsy. The compound is known to induce generalized seizures, providing a valuable tool for studying the pathophysiology of epilepsy and for screening the efficacy of potential anti-seizure medications. By carefully controlling the dosage and administration of L-Allylglycine, researchers can reliably generate seizure activity, facilitating the discovery and development of new treatments for epilepsy. This underlines the importance of being able to buy L-Allylglycine for translational research.
Beyond epilepsy, L-Allylglycine is also employed to investigate other neurological conditions characterized by GABAergic dysfunction. Its effects on locomotor activity and attention suggest its utility in studying disorders involving impaired motor control or cognitive deficits. By observing how L-Allylglycine influences these behavioral parameters, scientists can gain deeper insights into the neural mechanisms underlying these complex symptoms, thereby expanding the spectrum of L-Allylglycine applications in neuroscience.
For academic and pharmaceutical researchers, L-Allylglycine represents more than just a chemical reagent; it is a key that unlocks a deeper understanding of brain function and dysfunction. Its consistent and predictable effects make it a reliable component in experimental designs aimed at elucidating disease mechanisms and identifying novel therapeutic targets. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the scientific community by providing high-quality L-Allylglycine, empowering researchers to make significant advancements in the fight against neurological diseases.
Perspectives & Insights
Nano Explorer 01
“This underlines the importance of being able to buy L-Allylglycine for translational research.”
Data Catalyst One
“Beyond epilepsy, L-Allylglycine is also employed to investigate other neurological conditions characterized by GABAergic dysfunction.”
Chem Thinker Labs
“Its effects on locomotor activity and attention suggest its utility in studying disorders involving impaired motor control or cognitive deficits.”