N-Carbethoxy-4-piperidone, identified by CAS number 29976-53-2, is a chemical compound that holds significant value in the pharmaceutical and fine chemical industries. Understanding its detailed properties, purity requirements, and the best practices for purchasing is crucial for researchers, formulators, and procurement specialists. As a key intermediate, its quality directly impacts the efficacy and safety of the final drug products.

Physically, N-Carbethoxy-4-piperidone is typically described as a clear, colorless to pale yellow liquid. Its molecular formula is C8H13NO3, with a molecular weight of approximately 171.19 g/mol. The compound's reactivity is influenced by the presence of both a carbonyl group and an ethoxycarbonyl substituent within its piperidone ring structure. These features make it a versatile reagent for various organic transformations, including the synthesis of complex heterocyclic compounds.

In terms of purity, pharmaceutical applications often demand a high assay, commonly ≥98.0%. This level of purity ensures minimal interference from impurities during synthesis, leading to higher yields and purer final products. For instance, when used as an intermediate for drugs like Domperidone or Cisapride, or as a reference standard like Loratadine EP Impurity H, consistent high purity is non-negotiable. Buyers should always verify the purity specifications provided by the manufacturer.

When it comes to purchasing N-Carbethoxy-4-piperidone, particularly from international markets like China, it is advisable to collaborate with established manufacturers. These suppliers can offer competitive pricing, especially for bulk orders, and typically adhere to stringent quality control protocols. Key considerations when selecting a supplier include their manufacturing capabilities, responsiveness, provision of comprehensive documentation (CoA, MSDS), and their track record in delivering on time.

The market for N-Carbethoxy-4-piperidone also sees its use in research for novel therapeutic agents, suggesting its ongoing relevance in drug discovery. For businesses aiming to buy this compound, engaging with manufacturers that specialize in pharmaceutical intermediates is recommended. This ensures you receive a product that not only meets chemical specifications but also aligns with the rigorous standards of the pharmaceutical industry. By carefully evaluating suppliers and understanding product requirements, procurement teams can secure a reliable source for this important chemical.