NINGBO INNO PHARMCHEM CO., LTD. is dedicated to advancing the field of chemical synthesis by providing essential building blocks. One such compound is 4-Amino-2-fluorobenzonitrile (CAS 53312-80-4), a versatile intermediate with broad applications in organic chemistry. This article delves into its key properties, synthesis, and the importance of sourcing it from reliable manufacturers.

The chemical structure of 4-Amino-2-fluorobenzonitrile is characterized by a benzonitrile ring substituted with both an amino group and a fluorine atom. This unique combination grants it specific reactivity and stability, making it highly valuable. Its physical form is typically an off-white to yellow powder. The compound exhibits a density of around 1.3 g/cm³, a boiling point of approximately 288.2 °C, and a flash point of 128.1 °C, indicating moderate flammability. The low vapor pressure of 0.0 mmHg at 25°C suggests it is a stable compound with low volatility, making it suitable for various industrial processes. These properties collectively make it a reliable choice for synthesis projects.

The primary role of 4-Amino-2-fluorobenzonitrile is as an intermediate in organic synthesis. It serves as a crucial building block for more complex molecules, particularly within the pharmaceutical and agrochemical industries. Its fluorine atom can enhance the metabolic stability and bioavailability of drug candidates, leading to improved therapeutic outcomes. Similarly, in agrochemicals, it contributes to the development of advanced crop protection agents. The presence of both a nitrile and an amino group allows for diverse chemical transformations, such as hydrolysis, reduction, and further functionalization, expanding its synthetic utility.

Production of 4-Amino-2-fluorobenzonitrile involves precise organic synthesis methods. Ensuring high purity, typically ≥98.0%, is a critical aspect of its manufacturing. This high standard is crucial for its application in sensitive synthesis pathways, particularly for pharmaceutical intermediates. Manufacturers in China have become prominent suppliers, optimizing production techniques to meet global demand. Choosing a trusted 4-Amino-2-fluorobenzonitrile supplier ensures consistent quality and reliable delivery, which is vital for uninterrupted research and production cycles.

Proper storage is essential to maintain the compound's efficacy. It should be stored in a cool, well-ventilated place, shielded from light and moisture. Its low volatility reduces risks associated with airborne exposure, but standard laboratory safety practices, including the use of personal protective equipment, should always be followed. Packaging is often provided in 25 kg drums or tailored to specific customer requirements, reflecting the flexibility offered by leading suppliers. The market demand for 4-Amino-2-fluorobenzonitrile continues to grow, driven by its indispensable role in advancing chemical science and product development.

NINGBO INNO PHARMCHEM CO., LTD. is equipped to meet your needs for high-quality 4-Amino-2-fluorobenzonitrile. We also offer comprehensive custom synthesis services, leveraging our expertise in complex reaction chemistry. If you are seeking to purchase 4-Amino-2-fluorobenzonitrile or require specialized chemical solutions, please reach out to us for a consultation. We are committed to supporting your innovation and production goals with superior chemical products and services.