In the realm of organic chemistry, certain intermediates serve as linchpins for synthesizing a vast array of complex molecules. 2-(Trifluoromethoxy)benzoyl Chloride is one such compound, prized for its reactivity and the unique properties it introduces into organic frameworks. This article explores its physical characteristics, chemical behavior, and diverse applications, highlighting its importance for researchers and manufacturers.

Understanding 2-(Trifluoromethoxy)benzoyl Chloride

Identified by CAS Number 162046-61-9, 2-(Trifluoromethoxy)benzoyl Chloride is an aromatic acyl chloride. Its molecular formula is C8H4ClF3O2, and it has a molecular weight of 224.564. Physically, it presents as a yellow transparent liquid, a critical detail for handling and identification.

Key physical and chemical properties include:

  • Appearance: Yellow transparent liquid
  • Boiling Point: Approximately 94°C
  • Flash Point: 94-96°C
  • Density: 1.44 g/mL
  • Refractive Index: 1.47
  • Assay: ≥98.0%
  • Moisture Content: ≤0.2%

These specifications, particularly the high assay and low moisture content, are crucial for R&D scientists and procurement managers who require dependable inputs for their synthesis processes. Consistent quality ensures reproducible results and efficient manufacturing.

Versatile Applications in Organic Synthesis

The primary utility of 2-(Trifluoromethoxy)benzoyl Chloride lies in its function as an acylating agent. The presence of the highly electronegative trifluoromethoxy group (-OCF3) influences the reactivity of the carbonyl chloride. Its applications span several key industries:

  • Pharmaceuticals: It is a vital intermediate in synthesizing active pharmaceutical ingredients (APIs), particularly those designed for enhanced lipophilicity and metabolic stability, improving drug efficacy.
  • Agrochemicals: It serves as a building block for modern herbicides and fungicides, contributing to improved pest control and crop yields.
  • Material Science: The compound is employed in the creation of advanced polymers and coatings that require superior thermal and chemical stability.
  • Research and Development: It is invaluable for academic and industrial researchers exploring novel fluorinated compounds and their potential applications.

Sourcing and Availability

As a leading manufacturer and supplier in China, we provide high-quality 2-(Trifluoromethoxy)benzoyl Chloride to global markets. We understand the importance of reliable sourcing for innovation. Our commitment is to offer this essential intermediate at competitive prices, ensuring that researchers and manufacturers can easily buy the quantities they need for their projects.

In summary, 2-(Trifluoromethoxy)benzoyl Chloride is a remarkably versatile and important chemical intermediate. Its well-defined properties and broad applicability make it an indispensable component for advancements in pharmaceuticals, agrochemicals, and material science, underscoring its significance in the fine chemical industry.