Exploring the Synthesis and Applications of 3-Fluoroaniline in Organic Chemistry
Organic chemistry is a dynamic field driven by the synthesis of novel molecules with unique properties. 3-Fluoroaniline (CAS 372-19-0) stands as a versatile and important intermediate, finding widespread use in various synthetic endeavors. Its specific structural attributes, namely the meta-positioned fluorine atom on the aniline ring, grant it distinct reactivity patterns that chemists leverage for building complex organic structures. NINGBO INNO PHARMCHEM CO.,LTD. is a key provider of this essential reagent.
The chemical properties of 3-Fluoroaniline are well-documented. It is typically a liquid with a distinct color ranging from colorless to pale yellow. Its boiling point of around 186°C and a melting point of -2°C classify it as a liquid under standard laboratory conditions. The fluorine substituent electro-negativity influences the electron density of the aromatic ring, affecting its susceptibility to electrophilic aromatic substitution and other reactions. This makes it a valuable starting material for a plethora of organic transformations.
Synthesis of 3-Fluoroaniline often involves the reduction of 3-fluoronitrobenzene. This process typically employs reducing agents like hydrogen gas in the presence of a catalyst (e.g., palladium on carbon) or chemical reducing agents such as iron or tin in acidic media. The efficiency and purity of the final product are highly dependent on the chosen synthetic route and purification methods. For researchers looking to buy 3-Fluoroaniline, understanding these synthesis nuances can inform their choice of supplier.
The applications of 3-Fluoroaniline in organic synthesis are extensive. Beyond its roles in pharmaceuticals, agrochemicals, and dyes, it is also employed in the creation of specialty chemicals, monomers for advanced polymers, and as a reagent in academic research exploring new reaction methodologies. Its ability to participate in coupling reactions, nucleophilic substitutions, and as a scaffold for further functionalization makes it a cornerstone for many synthetic chemists.
As a leading supplier of organic intermediates, NINGBO INNO PHARMCHEM CO.,LTD. offers high-purity 3-Fluoroaniline (CAS 372-19-0) to the scientific community. We understand the demands of organic synthesis and ensure our product meets the required specifications for successful outcomes. We encourage chemists and research institutions to purchase 3-Fluoroaniline from us, benefiting from our reliable supply chain and competitive pricing. Partner with NINGBO INNO PHARMCHEM CO.,LTD. for your essential organic chemistry building blocks.
Perspectives & Insights
Silicon Analyst 88
“For researchers looking to buy 3-Fluoroaniline, understanding these synthesis nuances can inform their choice of supplier.”
Quantum Seeker Pro
“Beyond its roles in pharmaceuticals, agrochemicals, and dyes, it is also employed in the creation of specialty chemicals, monomers for advanced polymers, and as a reagent in academic research exploring new reaction methodologies.”
Bio Reader 7
“Its ability to participate in coupling reactions, nucleophilic substitutions, and as a scaffold for further functionalization makes it a cornerstone for many synthetic chemists.”