Bis(2-bromoacetyl)biphenyl, also known by its CAS number 4072-67-7, is a chemical compound that plays a significant role in various sectors, particularly in pharmaceutical intermediate synthesis and broader organic chemistry applications. As a reputable supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers this critical compound, facilitating innovation and production for researchers and manufacturers worldwide. This article delves into the synthesis, chemical properties, and diverse applications of this important molecule.

The synthesis of Bis(2-bromoacetyl)biphenyl typically involves a well-established chemical process. One common route starts with biphenyl, which undergoes Friedel-Crafts acylation to yield 4,4'-diacetylbiphenyl. This intermediate is then subjected to bromination, usually in acetic acid, to introduce the bromoacetyl groups. The resulting product, Bis(2-bromoacetyl)biphenyl, is then purified. The efficiency and purity achieved in these synthetic steps are crucial for its subsequent use, especially in pharmaceutical synthesis where stringent quality control is paramount. Understanding the nuances of the synthesis of Daclatasvir intermediate relies heavily on the quality of this precursor.

The chemical properties of Bis(2-bromoacetyl)biphenyl make it highly valuable. It typically appears as a white crystalline powder and possesses reactive bromoacetyl functional groups. These groups are susceptible to nucleophilic substitution, allowing for the attachment of various other molecules, thereby enabling the creation of more complex structures. This reactivity is central to its utility as an organic synthesis building block. Its molecular formula is C16H12Br2O2, with a molecular weight of approximately 396.07 g/mol. The compound is generally stable under appropriate storage conditions, which typically involve keeping it in a well-closed container away from moisture.

The applications of Bis(2-bromoacetyl)biphenyl are diverse and impactful. Its most recognized use is as a critical intermediate in the pharmaceutical industry for synthesizing antiviral drugs like Daclatasvir. Daclatasvir has been instrumental in the treatment of Hepatitis C, a significant global health concern. By providing a reliable source for this chemical intermediate, NINGBO INNO PHARMCHEM CO.,LTD. supports the production of life-saving medications. Furthermore, its utility extends to the synthesis of other specialty chemicals and materials, where its bifunctional nature can be exploited to create polymers or cross-linked networks. The demand for this compound as a chemical intermediate CAS 4072-67-7 highlights its fundamental importance in chemical manufacturing.

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying Bis(2-bromoacetyl)biphenyl that meets the highest industry standards. Our manufacturing processes in China are optimized for yield, purity, and consistency, ensuring that our clients receive a product they can depend on for their critical research and production needs. Whether you are involved in drug discovery, process optimization, or the development of novel materials, Bis(2-bromoacetyl)biphenyl from NINGBO INNO PHARMCHEM CO.,LTD. is a reliable choice.