Exploring the Synthesis and Applications of Bromoacetyl Bromide
Bromoacetyl Bromide (CAS 598-21-0) is a pivotal chemical intermediate renowned for its reactivity and versatility in organic synthesis. Its unique molecular structure and properties make it an indispensable reagent for chemists across various industries, particularly in the development of pharmaceuticals and agrochemicals. This article explores the fundamental aspects of Bromoacetyl Bromide, including its chemical characteristics, synthesis pathways, and its broad spectrum of applications, while also emphasizing the importance of sourcing from quality manufacturers like NINGBO INNO PHARMCHEM CO.,LTD.
Chemically known as bromoacetyl bromide or 2-bromoacetyl bromide, its molecular formula is C₂H₂Br₂O, with a molecular weight of approximately 201.84 g/mol. Physically, it is described as a colorless to yellowish liquid, possessing a density of 2.324 and a boiling point in the range of 147-150°C. These properties are indicative of its reactive nature and the care required during its handling and storage. The compound’s flash point of 105°C also provides crucial safety information for industrial use.
The synthesis of Bromoacetyl Bromide typically involves the bromination of acetyl bromide or related precursors. While specific industrial processes may vary, the goal is to achieve high purity, often specified as ≥98.0%, with minimal moisture content (≤0.1%). This commitment to purity is essential, as impurities can lead to undesirable side reactions, reduced yields, and compromised quality in downstream applications. For those seeking to buy Bromoacetyl Bromide, understanding these specifications is the first step towards successful integration into their processes.
The utility of Bromoacetyl Bromide in organic synthesis is vast. It acts as a key reagent for introducing the bromoacetyl group into organic molecules. This functional group is highly reactive and can participate in numerous transformations, including nucleophilic substitutions, esterifications, and amidations. In the pharmaceutical sector, it is used to synthesize key intermediates for a wide range of APIs, contributing to the development of vital medicines. Its role in creating α-bromo carbonyl compounds, which are precursors to β-lactams and amino acid derivatives, is particularly noteworthy.
In the agrochemical industry, Bromoacetyl Bromide is employed in the synthesis of pesticides, such as herbicides and insecticides. Its reactive bromine atom can be incorporated into molecules designed to target specific biological pathways in pests or weeds. The compound’s ability to enhance molecular structure and reactivity makes it invaluable for creating advanced crop protection agents.
Beyond these major applications, Bromoacetyl Bromide also finds use in the synthesis of performance chemicals and as a building block for various heterocyclic compounds. Its versatility makes it a staple intermediate for fine chemical manufacturers.
When considering the procurement of Bromoacetyl Bromide, partnering with a reliable supplier is paramount. NINGBO INNO PHARMCHEM CO.,LTD., a leading chemical manufacturer in China, offers high-quality Bromoacetyl Bromide. Their dedication to stringent quality control, competitive pricing, and efficient logistics makes them an ideal partner for companies worldwide that require this essential chemical intermediate. Ensuring a stable supply chain of high-purity Bromoacetyl Bromide from a trusted manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is key to maintaining operational efficiency and product quality.
In conclusion, Bromoacetyl Bromide is a powerful tool in the arsenal of organic chemists. Its diverse applications in pharmaceuticals, agrochemicals, and performance chemicals highlight its significance. By understanding its properties and sourcing it from reputable manufacturers, businesses can effectively leverage Bromoacetyl Bromide to drive innovation and achieve their synthesis objectives.
Chemically known as bromoacetyl bromide or 2-bromoacetyl bromide, its molecular formula is C₂H₂Br₂O, with a molecular weight of approximately 201.84 g/mol. Physically, it is described as a colorless to yellowish liquid, possessing a density of 2.324 and a boiling point in the range of 147-150°C. These properties are indicative of its reactive nature and the care required during its handling and storage. The compound’s flash point of 105°C also provides crucial safety information for industrial use.
The synthesis of Bromoacetyl Bromide typically involves the bromination of acetyl bromide or related precursors. While specific industrial processes may vary, the goal is to achieve high purity, often specified as ≥98.0%, with minimal moisture content (≤0.1%). This commitment to purity is essential, as impurities can lead to undesirable side reactions, reduced yields, and compromised quality in downstream applications. For those seeking to buy Bromoacetyl Bromide, understanding these specifications is the first step towards successful integration into their processes.
The utility of Bromoacetyl Bromide in organic synthesis is vast. It acts as a key reagent for introducing the bromoacetyl group into organic molecules. This functional group is highly reactive and can participate in numerous transformations, including nucleophilic substitutions, esterifications, and amidations. In the pharmaceutical sector, it is used to synthesize key intermediates for a wide range of APIs, contributing to the development of vital medicines. Its role in creating α-bromo carbonyl compounds, which are precursors to β-lactams and amino acid derivatives, is particularly noteworthy.
In the agrochemical industry, Bromoacetyl Bromide is employed in the synthesis of pesticides, such as herbicides and insecticides. Its reactive bromine atom can be incorporated into molecules designed to target specific biological pathways in pests or weeds. The compound’s ability to enhance molecular structure and reactivity makes it invaluable for creating advanced crop protection agents.
Beyond these major applications, Bromoacetyl Bromide also finds use in the synthesis of performance chemicals and as a building block for various heterocyclic compounds. Its versatility makes it a staple intermediate for fine chemical manufacturers.
When considering the procurement of Bromoacetyl Bromide, partnering with a reliable supplier is paramount. NINGBO INNO PHARMCHEM CO.,LTD., a leading chemical manufacturer in China, offers high-quality Bromoacetyl Bromide. Their dedication to stringent quality control, competitive pricing, and efficient logistics makes them an ideal partner for companies worldwide that require this essential chemical intermediate. Ensuring a stable supply chain of high-purity Bromoacetyl Bromide from a trusted manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is key to maintaining operational efficiency and product quality.
In conclusion, Bromoacetyl Bromide is a powerful tool in the arsenal of organic chemists. Its diverse applications in pharmaceuticals, agrochemicals, and performance chemicals highlight its significance. By understanding its properties and sourcing it from reputable manufacturers, businesses can effectively leverage Bromoacetyl Bromide to drive innovation and achieve their synthesis objectives.
Perspectives & Insights
Silicon Analyst 88
“In the pharmaceutical sector, it is used to synthesize key intermediates for a wide range of APIs, contributing to the development of vital medicines.”
Quantum Seeker Pro
“Its role in creating α-bromo carbonyl compounds, which are precursors to β-lactams and amino acid derivatives, is particularly noteworthy.”
Bio Reader 7
“In the agrochemical industry, Bromoacetyl Bromide is employed in the synthesis of pesticides, such as herbicides and insecticides.”