NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting the cutting edge of drug discovery by supplying high-quality chemical intermediates. One such critical compound is Boc-2-bromo-L-phenylalanine (CAS 261165-02-0), a derivative of phenylalanine that offers remarkable versatility for medicinal chemists and researchers in drug development.

The primary utility of Boc-2-bromo-L-phenylalanine lies in its dual functionality. The N-terminal BOC protection group facilitates controlled peptide synthesis, preventing premature reactions at the amine site. This is crucial when building complex peptide sequences or incorporating modified amino acids into a peptide chain. The bromine atom, located on the phenyl ring, provides a strategic site for subsequent chemical modifications. This capability is invaluable in drug discovery, allowing for the introduction of various functional groups through reactions like palladium-catalyzed cross-couplings. These modifications can fine-tune the pharmacological properties of a molecule, such as its binding affinity, metabolic stability, or bioavailability.

Medicinal chemists frequently utilize Boc-2-bromo-L-phenylalanine as a scaffold to construct novel compounds with potential therapeutic activity. By systematically altering the substituents introduced via the bromine atom, researchers can explore vast chemical spaces to identify lead compounds for drug candidates. The chiral nature of the L-phenylalanine backbone is also important, as stereochemistry often plays a critical role in a drug's efficacy and safety. When considering the purchase of Boc-2-bromo-L-phenylalanine, the purity and reliable sourcing from established suppliers like NINGBO INNO PHARMCHEM CO.,LTD. are paramount to ensure the reproducibility of synthetic efforts and the validity of screening results.

The price of Boc-2-bromo-L-phenylalanine can vary depending on the supplier and quantity, but its contribution to streamlining the drug discovery process often justifies the investment. Its applications extend beyond direct peptide synthesis; it can be used in the creation of small molecule inhibitors, probes, and other biologically relevant molecules. Understanding the chemical properties of Boc-2-bromo-L-phenylalanine, including its solubility and reactivity, allows researchers to design efficient synthetic routes.

In summary, Boc-2-bromo-L-phenylalanine serves as a pivotal intermediate in drug discovery, offering chemists a flexible platform for innovation. Its well-defined structure, reactive bromine atom, and protective BOC group make it an essential reagent for synthesizing novel therapeutics. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply this critical compound, supporting the vital work of medicinal chemists worldwide.