2-Piperidone, a compound often referred to as 5-pentanelactam, is a chemical entity of significant importance in the field of organic synthesis and pharmaceutical manufacturing. Identified by its CAS number 675-20-7, this cyclic amide possesses a unique set of chemical properties that make it a highly sought-after intermediate. Its molecular formula, C5H9NO, and a molecular weight of approximately 99.131, provide a foundation for its reactivity and utility in various chemical processes. Understanding these characteristics is crucial for researchers and manufacturers aiming to leverage its potential.

One of the key attributes of 2-Piperidone is its physical state, which can range from a light yellow liquid to a crystalline solid, with a melting point typically between 38-40°C. Its boiling point, around 256-262°C, indicates a degree of thermal stability. Furthermore, its solubility in water, at approximately 291 g/L at 25°C, is notably high, which is advantageous for reactions conducted in aqueous media or for purification processes. This excellent water solubility, coupled with a LogP value of -0.45, underscores its hydrophilic nature, further enhancing its applicability in diverse chemical environments.

The chemical versatility of 2-Piperidone is perhaps its most defining feature. As a pharmaceutical intermediate, it serves as a critical building block in the synthesis of complex drug molecules. Its most prominent application is in the production of apixaban, an anticoagulant that has revolutionized the treatment of blood clots. The lactam ring within its structure is susceptible to various chemical modifications, allowing for the introduction of different functional groups and the construction of more intricate molecular frameworks. This makes 2-Piperidone an invaluable asset in drug discovery and development pipelines.

Beyond its pharmaceutical applications, 2-Piperidone also finds utility in the broader fine chemical industry. Its ability to participate in a range of reactions makes it a versatile starting material for the synthesis of various organic compounds. Sourcing high-purity 2-Piperidone, typically with an assay of ≥99.0%, is a standard requirement for most applications to ensure the integrity and efficiency of downstream processes. For businesses seeking reliable 2-Piperidone suppliers, NINGBO INNO PHARMCHEM CO.,LTD. is a distinguished manufacturer in China that consistently delivers on quality and availability, supporting a wide spectrum of chemical synthesis needs.