1,2-Cyclohexanediol, identified by CAS number 931-17-9, is a compound of significant interest within the chemical industry due to its versatile chemical properties and broad applicability. As a cycloaliphatic diol, it serves as a fundamental building block in numerous organic synthesis processes, ranging from the development of pharmaceuticals to the creation of advanced materials. Understanding its chemical characteristics and the methods employed for its synthesis is crucial for researchers and manufacturers alike.

The chemical properties of 1,2-cyclohexanediol are well-documented. It typically presents as a white to off-white crystalline powder, with a melting point range of 73-77°C and a boiling point of 118-120°C at 10 mmHg. A key characteristic is its solubility in water, which facilitates its use in various aqueous reaction systems. The compound also exists in two stereoisomeric forms: cis and trans. The trans isomer, in particular, is often studied for its distinct chemical behavior and potential applications in stereoselective synthesis. Researchers investigating 1,2-cyclohexanediol synthesis methods often focus on efficiency and purity, employing techniques such as the catalytic hydrogenation of catechol or the direct dihydroxylation of cyclohexene. These synthetic pathways are optimized to yield high-purity 1,2-cyclohexanediol, ensuring its suitability for demanding applications.

The applications of 1,2-cyclohexanediol are diverse and impactful. Its primary use as a pharmaceutical intermediate underscores its importance in drug discovery and development. Beyond pharmaceuticals, it finds utility in polymer science, where it can be incorporated to modify material properties, and in general organic synthesis as a valuable precursor. The chemical industry relies on a stable supply of this compound, making research into cost-effective and environmentally friendly 1,2-cyclohexanediol synthesis methods a continuous endeavor. The exploration of its stereoisomers, especially the trans form, opens avenues for creating complex chiral molecules, essential in fields like enantioselective catalysis and the synthesis of chiral drugs. The detailed examination of 1,2-cyclohexanediol's chemical properties is fundamental for anyone working with this compound, from laboratory research to industrial-scale production. NINGBO INNO PHARMCHEM CO.,LTD. remains committed to providing access to high-quality 1,2-cyclohexanediol, supporting innovation across the chemical sciences.