2,5-Dibromo-3-nitropyridine (CAS: 15862-37-0) is a fascinating molecule that holds significant value for synthetic chemists due to its distinct chemical properties and versatile reactivity. As a key intermediate, understanding its structural nuances is crucial for maximizing its utility in pharmaceutical, agrochemical, and materials science applications. This exploration delves into the chemical characteristics that make this pyridine derivative a powerful tool for innovation.

The core of 2,5-Dibromo-3-nitropyridine's utility lies in its functional groups and their strategic placement on the pyridine ring. The presence of two bromine atoms, one at the 2-position and another at the 5-position, offers excellent sites for nucleophilic substitution and transition-metal-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Heck couplings. These reactions allow for the introduction of a wide variety of carbon-based fragments, enabling the construction of complex carbon skeletons. The nitro group at the 3-position is a strong electron-withdrawing group, which not only influences the reactivity of the ring but can also be further transformed, for example, through reduction to an amine group, opening up additional synthetic pathways.

The compound's stability, when stored under recommended conditions (e.g., cool, dry, and inert atmosphere), is also a significant advantage for researchers and manufacturers. Its typical appearance as a yellow solid, with a melting point often in the range of 92-96 °C, provides a tangible characteristic for identification. The molecular formula, C5H2Br2N2O2, and a molecular weight of approximately 281.89 g/mol, are fundamental data points for stoichiometric calculations in any synthesis endeavor.

For professionals looking to buy 2,5-dibromo-3-nitropyridine, it is essential to procure from a reliable supplier that can guarantee the specified purity, often exceeding 95% or 98% by GC. This ensures that the intended reactions proceed efficiently without interference from impurities. Whether you are engaged in drug discovery, developing next-generation pesticides, or exploring novel materials, the consistent quality of this intermediate is foundational. Investigating the price from different manufacturers can help optimize procurement budgets, especially for bulk purchases.

The integration of 2,5-Dibromo-3-nitropyridine into synthesis schemes allows for the creation of sophisticated heterocyclic compounds. Its utility as a pharmaceutical intermediate is well-documented, contributing to the development of diverse therapeutic agents. Similarly, its role in agrochemical synthesis aids in producing more targeted and effective crop protection agents. As research progresses, the exploration of its full chemical potential continues, solidifying its status as a critical component in the synthetic chemist's toolkit. When sourcing this essential compound, partnering with a trusted 2,5-dibromo-3-nitropyridine manufacturer ensures access to quality materials and expert support.