Exploring the Chemical Synthesis of 2-Bromo-N-isopropylacetamide: A Key Intermediate
The synthesis of essential chemical intermediates is the backbone of many industries, particularly pharmaceuticals and fine chemicals. 2-Bromo-N-isopropylacetamide (CAS 75726-96-4) is a prime example of such a critical compound, valued for its role in complex organic transformations. Understanding its production pathway and chemical properties is key to appreciating its significance.
The typical synthetic route for 2-Bromo-N-isopropylacetamide involves the reaction between isopropylamine and bromoacetyl bromide. This reaction, often carried out under controlled conditions, efficiently produces the desired amide. The choice of solvent, temperature, and reactant stoichiometry are carefully managed to ensure a high yield and purity of the final product, which is usually obtained as a white solid. This method of synthesis is fundamental to providing a reliable supply of this important intermediate.
NINGBO INNO PHARMCHEM CO.,LTD. specializes in the production and supply of high-quality 2-Bromo-N-isopropylacetamide. Our expertise in chemical synthesis ensures that we adhere to rigorous quality control measures throughout the manufacturing process. This commitment guarantees that our clients receive a product that meets their exacting standards for purity and reactivity, essential for their downstream applications.
The chemical properties of 2-Bromo-N-isopropylacetamide, such as its melting point of approximately 63-64°C and its reactive bromoacetyl group, make it highly versatile. This inherent reactivity is what makes it an attractive component in various pharmaceutical intermediate synthesis pathways. The ability to predictably engage in substitution reactions allows chemists to build complex molecular frameworks with precision.
For those involved in drug discovery, the CAS 75726-96-4 serves as a vital link in the chain. Its role in creating molecules like Belumosudil showcases its therapeutic relevance. Ensuring a stable supply of this intermediate is crucial for maintaining the momentum of research and development in the pharmaceutical sector.
The process of understanding isopropylamine bromoacetyl bromide reaction informs not only the production but also the potential applications of 2-Bromo-N-isopropylacetamide. By mastering these synthetic techniques, companies like NINGBO INNO PHARMCHEM CO.,LTD. can efficiently deliver the chemical building blocks that power innovation across various scientific disciplines.
In summary, 2-Bromo-N-isopropylacetamide is a strategically important fine chemical intermediate. Its synthesis from readily available precursors and its versatile reactivity make it indispensable. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this compound with the utmost quality, supporting the critical work of chemists and manufacturers worldwide.
Perspectives & Insights
Logic Thinker AI
“The typical synthetic route for 2-Bromo-N-isopropylacetamide involves the reaction between isopropylamine and bromoacetyl bromide.”
Molecule Spark 2025
“This reaction, often carried out under controlled conditions, efficiently produces the desired amide.”
Alpha Pioneer 01
“The choice of solvent, temperature, and reactant stoichiometry are carefully managed to ensure a high yield and purity of the final product, which is usually obtained as a white solid.”