4'-Chloropropiophenone, identified by its CAS number 6285-05-8, is a chemical compound of significant interest across various industrial sectors due to its versatile properties and applications. As an aromatic ketone, it features a benzene ring substituted with a chlorine atom at the para position, and a propiophenone functional group. This specific molecular architecture dictates its chemical behavior and utility as a crucial intermediate in organic synthesis.

Physical and Chemical Characteristics

Typically supplied as a white crystalline solid or a pale yellow liquid, 4'-Chloropropiophenone exhibits a melting point in the range of 35-37 °C. Its molecular formula is C9H9ClO, with a molecular weight of 168.62 g/mol. Chemically, it is known for its reactivity, particularly in electrophilic aromatic substitution reactions due to the presence of the activating alkyl ketone group and the deactivating but ortho, para-directing chlorine atom on the phenyl ring. This dual nature makes it amenable to a variety of synthetic transformations.

Key Industrial Applications

The primary utility of 4'-Chloropropiophenone lies in its role as a chemical intermediate. Its most prominent applications include:

  • Pharmaceutical Synthesis: It serves as a vital precursor in the production of various Active Pharmaceutical Ingredients (APIs), notably in the development of analgesics and anti-inflammatory drugs. Its structure allows for the precise modification needed to achieve desired therapeutic effects. For those looking to buy this compound for pharmaceutical manufacturing, sourcing from a reputable China manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures high purity (typically ≥97.8%) and reliability.
  • Fragrance Industry: 4'-Chloropropiophenone contributes to the formulation of fragrances and perfumes, imparting unique scent profiles that enhance product appeal. Its subtle aroma can add depth and complexity to scent compositions.
  • Polymer Chemistry: In the realm of polymer science, this compound can act as a photoinitiator, improving the efficiency of UV-cured coatings and adhesives.
  • General Organic Synthesis: Researchers and industrial chemists utilize it as a fundamental building block in various organic synthesis pathways for creating specialty chemicals and exploring new chemical reactions.

Where to Buy 4'-Chloropropiophenone

When sourcing 4'-Chloropropiophenone, particularly for industrial applications, it is essential to find a dependable supplier. Businesses frequently search for '4'-Chloropropiophenone supplier China' or inquire about the 'price of 4'-Chloropropiophenone'. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier, offering high-purity material and competitive pricing for bulk purchases. Ensuring consistent quality and reliable delivery is paramount for companies engaged in large-scale manufacturing or critical research projects.

In essence, 4'-Chloropropiophenone is a foundational chemical intermediate with broad applicability. Its unique properties make it indispensable for industries ranging from pharmaceuticals to fragrances, underscoring the importance of sourcing it from trusted and experienced chemical manufacturers.