Methoxycarbonyl-L-tert-leucine (CAS: 162537-11-3) is a meticulously synthesized chemical compound that plays a significant role in the pharmaceutical industry as a key intermediate.

Characterized as a white to off-white powder, it possesses a defined melting point of approximately 109u00b0C and a boiling point of around 320.9u00b0C. Its density is approximately 1.126 g/cmu00b3, and it exhibits good solubility in organic solvents like ethyl acetate and methanol, properties that are vital for its application in various chemical reactions. The compound's high purity, typically u226598.5%, is a critical factor for its use in the synthesis of active pharmaceutical ingredients (APIs).

The primary application of Methoxycarbonyl-L-tert-leucine lies in its indispensable role in the synthesis of complex pharmaceuticals. It is particularly noted for its use in the production of Atazanavir sulfate, an essential drug for managing HIV infections. The synthesis process involves utilizing this intermediate in crucial coupling reactions that build the molecular framework of the drug. Similarly, it serves as a vital precursor in the manufacturing of Bortezomib, a proteasome inhibitor used in cancer therapy. These applications highlight its importance in developing treatments for serious global health challenges.

The consistent quality and supply of Methoxycarbonyl-L-tert-leucine are maintained by specialized chemical manufacturers. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on rigorous quality control measures to ensure the compound's integrity from production to delivery. Understanding these properties and applications is key for researchers and manufacturers aiming to leverage this compound for efficient and successful drug development, contributing to advancements in both HIV and cancer treatment protocols.