4,6-Dihydroxy-2-methylpyrimidine (CAS: 40497-30-1) is a compound whose chemical structure and reactivity make it a cornerstone for various advanced synthesis projects. Its significance is rooted in its role as a versatile intermediate, enabling the creation of complex molecules vital for human health and agricultural productivity.

The synthesis of 4,6-Dihydroxy-2-methylpyrimidine itself often involves the reaction of acetamidine hydrochloride with diethyl malonate. The process, as detailed in some literature, requires careful control of reaction conditions, including temperature and pH, to achieve good yields and purity. The resulting product, typically a yellow solid with a purity of 98.0% or higher, is then ready for its role as a building block.

The primary applications driving demand for this pyrimidine derivative are in the pharmaceutical and agrochemical sectors. In pharmaceuticals, it serves as a crucial intermediate in the synthesis of blockbuster drugs. For instance, its structure is foundational for creating Mosapride, a medication used to treat gastrointestinal disorders, and Dasatinib, a powerful targeted therapy for certain types of leukemia. Researchers and manufacturers in this field rely on a consistent and high-quality supply from a trusted manufacturer of pharmaceutical intermediates.

In the agrochemical industry, 4,6-Dihydroxy-2-methylpyrimidine contributes to the development of new and improved pesticides and herbicides. These compounds are essential for modern agriculture, helping to protect crops from pests and diseases, thereby ensuring higher yields and more stable food supplies. The precise chemical structure of this intermediate allows for modifications that can lead to more effective and environmentally conscious agrochemical solutions.

For companies aiming to leverage these applications, identifying a reliable supplier of CAS 40497-30-1 is key. Whether you are looking to buy 4,6-dihydroxy-2-methylpyrimidine for research and development or for large-scale commercial production, understanding the synthesis pathways and quality specifications ensures you are making an informed decision. Partnering with a manufacturer that offers both technical expertise and dependable supply is the most effective way to integrate this vital intermediate into your product pipeline.