N-(4-Oxocyclohexyl)phthalimide, bearing the CAS number 104618-32-8, is a compound recognized for its role as a key intermediate in various chemical syntheses. Its distinctive structure, featuring a phthalimide group attached to a cyclohexanone ring, imparts specific reactivity that is highly valuable in organic chemistry. Understanding its synthesis and reactivity is crucial for chemists looking to utilize it effectively in their research and production processes.

The synthesis of N-(4-Oxocyclohexyl)phthalimide typically involves the reaction of 4-aminocyclohexanone with phthalic anhydride, or alternatively, the oxidation of N-(4-hydroxycyclohexyl)phthalimide. One described synthetic route involves mixing 4-(phthalimido)cyclohexanol with ethyl acetate, sodium bromide, and TEMPO, followed by the addition of an aqueous sodium hypochlorite solution to achieve oxidation. The pH is adjusted with sodium bicarbonate, and the reaction is maintained at a controlled temperature. After work-up, the product is obtained as a white solid in high yield. This process highlights the careful control required for efficient production, and many suppliers, particularly manufacturers in China, have optimized these methods to ensure high purity (u226598.0%) and consistent product quality.

The chemical reactivity of N-(4-Oxocyclohexyl)phthalimide is multifaceted. The carbonyl group of the cyclohexanone ring is susceptible to nucleophilic attack, reduction, and condensation reactions. The phthalimide group, known for its ability to protect amines, can be deprotected under specific conditions to liberate the amine functionality. This dual reactivity makes it an attractive starting material for a wide array of organic transformations. Researchers often seek information by searching for terms like 'organic synthesis building blocks' or 'pharmaceutical synthesis reagents' to find compounds like N-(4-Oxocyclohexyl)phthalimide that offer versatile reaction pathways.

For those looking to buy N-(4-Oxocyclohexyl)phthalimide, understanding its synthesis and potential reactions allows for better planning and execution of synthetic strategies. Whether it's for producing pharmaceutical intermediates or novel organic compounds, the quality and availability of this chemical are paramount. When comparing suppliers, factors such as the price of N-(4-Oxocyclohexyl)phthalimide, the purity specifications, and the reliability of the supply chain should be carefully evaluated. Accessing this intermediate from a trusted manufacturer ensures that the synthetic processes are built on a solid foundation of quality materials.

In summary, N-(4-Oxocyclohexyl)phthalimide is a compound whose synthesis and reactivity are central to its value in the chemical industry. Its controlled production yields a high-purity intermediate vital for advanced organic chemistry and pharmaceutical applications. By understanding its chemical behavior and sourcing it from reputable suppliers, scientists can effectively leverage its potential to drive innovation.