Procurement professionals in the chemical and pharmaceutical sectors constantly seek reliable sources for critical intermediates. 3,4,5-Trimethoxybenzoic Acid (CAS 118-41-2), also known by synonyms like Gallic acid trimethyl ether, is a compound with significant utility. This guide focuses on how buyers can effectively source this essential chemical, ensuring quality and value.

What is 3,4,5-Trimethoxybenzoic Acid?

3,4,5-Trimethoxybenzoic Acid is an organic compound characterized by a benzoic acid structure with three methoxy (-OCH3) groups at the 3, 4, and 5 positions. It typically appears as a white crystalline powder, with a purity level commonly specified as 97% or higher. Its molecular formula is C10H12O5, and its CAS number is 118-41-2.

Key Applications Driving Demand

The demand for 3,4,5-Trimethoxybenzoic Acid is fueled by its critical roles in several industries:

  • Pharmaceutical Synthesis: It serves as a vital intermediate in the creation of Active Pharmaceutical Ingredients (APIs). Its structural features are often incorporated into drugs targeting various conditions, making it indispensable for pharmaceutical R&D and manufacturing. Companies often look to buy 3,4,5-trimethoxybenzoic acid for its purity and suitability in complex synthesis routes.
  • Organic Synthesis: As a versatile building block, it is widely used in academic and industrial organic synthesis labs to create diverse chemical compounds. Its reactivity allows for a wide range of transformations.
  • Research and Development: Beyond synthesis, it's used in analytical chemistry as a reference standard and in other research applications due to its stable properties.
  • Other Industrial Uses: Historically, similar compounds have found uses in dyes, inks, and as astringents, indicating broader potential.

Procurement Best Practices for Buyers

For B2B buyers, securing a consistent supply of high-quality 3,4,5-Trimethoxybenzoic Acid involves several key steps:

  • Supplier Vetting: Prioritize working with established 3,4,5-trimethoxybenzoic acid manufacturers and chemical distributors. Thoroughly research potential suppliers, paying attention to their reputation, industry experience, and location (e.g., China for competitive sourcing).
  • Quality Assurance: Always request a Certificate of Analysis (CoA) to verify the product's purity (typically ≥97%) and ensure it meets your specific application requirements. Understanding the analytical methods used (e.g., HPLC) is also beneficial.
  • Price Negotiation: Obtain quotes from multiple suppliers to compare the CAS 118-41-2 price. Negotiate terms for bulk orders to achieve cost efficiencies.
  • Sample Evaluation: It is standard practice to request a free sample for testing before committing to a large-scale purchase. This allows you to confirm product quality and compatibility with your processes.
  • Logistics and Support: Confirm packaging options, lead times, and the supplier's ability to provide necessary regulatory documentation or technical support.

In essence, 3,4,5-Trimethoxybenzoic Acid is a valuable chemical intermediate with significant applications, particularly in pharmaceuticals and organic synthesis. By adopting a diligent and strategic approach to sourcing, procurement professionals can ensure they partner with reliable suppliers and obtain this critical compound at competitive prices and the highest quality standards.