The field of fine chemical synthesis relies heavily on versatile building blocks that facilitate the creation of complex molecules with specific functionalities. Tert-Butyl 3-oxobutanoate, known by its CAS number 1694-31-1, is a prime example of such a compound. With a molecular formula of C8H14O3 and a molecular weight of 158.20 g/mol, this beta-keto ester offers a unique combination of reactivity and a cleavable protecting group, making it invaluable for chemists in various industrial sectors. This article explores the applications of tert-Butyl 3-oxobutanoate in fine chemical synthesis and guides you on how to source it effectively.

The Chemical Versatility of Tert-Butyl 3-Oxobutanoate

Tert-Butyl 3-oxobutanoate’s utility in fine chemical synthesis is attributed to its beta-keto ester structure. The presence of both a ketone and an ester group allows it to undergo a wide range of chemical transformations. It is frequently employed in alkylation reactions at the alpha-carbon position, enabling the introduction of various functional groups. Furthermore, the tert-butyl ester can be readily hydrolyzed or cleaved under specific conditions, releasing the acetoacetic acid derivative, which can then be decarboxylated. This strategic flexibility makes it an ideal intermediate for synthesizing complex organic molecules, including specialty chemicals, flavorings, and fragrances, as well as intermediates for agrochemicals and pharmaceuticals.

Sourcing Strategies for Fine Chemical Manufacturers

For fine chemical manufacturers, securing a reliable and cost-effective supply of intermediates like tert-Butyl 3-oxobutanoate (CAS 1694-31-1) is critical for maintaining production efficiency and profitability. China, with its extensive chemical manufacturing infrastructure, is a key global supplier for such compounds. When looking to buy tert-Butyl 3-oxobutanoate, it is advisable to identify manufacturers who can consistently deliver high-purity material (typically 97% or higher) and have established quality management systems. Requesting a Certificate of Analysis (CoA) is standard practice to confirm the product's specifications and purity. Investigating suppliers' production capacities and their experience in exporting fine chemicals will also be beneficial.

Key Considerations for Buyers

When procuring tert-Butyl 3-oxobutanoate, several factors deserve careful attention. Beyond purity, understanding the supplier's lead times, minimum order quantities (MOQs), and packaging options is important. Many manufacturers offer different grades or purities, so clearly specifying your requirements, such as for synthesis applications that demand high reactivity, is crucial. Competitive pricing is also a significant driver, especially for bulk purchases. Therefore, obtaining quotes from multiple Chinese manufacturers and suppliers for CAS 1694-31-1 can help you identify the best value proposition. Ensure that the supplier can provide the necessary safety data sheets (SDS) and technical documentation.

Leveraging Tert-Butyl 3-Oxobutanoate in Your Synthesis

Incorporating tert-Butyl 3-oxobutanoate into your fine chemical synthesis processes can lead to more efficient routes and novel compound discoveries. Its predictable reactivity and the presence of the tert-butyl protecting group make it an attractive choice for chemists designing complex synthetic pathways. By partnering with a dependable manufacturer and supplier, you ensure that this essential intermediate is readily available, allowing your R&D and production teams to focus on innovation and output.

In summary, tert-Butyl 3-oxobutanoate (CAS 1694-31-1) is a cornerstone intermediate in fine chemical synthesis. Strategic sourcing from reliable manufacturers, particularly those in China, ensures access to high-quality material at competitive prices, thereby supporting the advancement of chemical manufacturing and product development.