Fine Chemicals Focus: Understanding N-Carbobenzyloxy-L-aspartic Acid (CAS 1152-61-0)
The realm of fine chemicals is characterized by high-purity substances produced in smaller quantities for specialized applications. N-Carbobenzyloxy-L-aspartic acid (CAS 1152-61-0) stands out as a prime example within this category, serving as an indispensable intermediate in various sophisticated chemical processes. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent manufacturer and supplier of this vital fine chemical.
N-Carbobenzyloxy-L-aspartic acid, also known as Z-Asp-OH, is a derivative of L-aspartic acid where the amino group is protected by the carbobenzyloxy (Cbz) moiety. This protection is crucial for preventing premature reactions and ensuring selectivity during complex multi-step syntheses. The compound typically presents as a white fine crystalline powder, with a melting point often cited around 117-119 °C. Its molecular formula is C12H13NO6, and it has a molecular weight of approximately 267.23 g/mol.
The synthesis of N-Carbobenzyloxy-L-aspartic acid is a well-established process. It typically begins with L-Aspartic acid, which is reacted with Benzyl chloroformate (Cbz-Cl) in an aqueous alkaline medium. This reaction selectively protects the alpha-amino group. Careful control of reaction conditions, followed by purification steps, yields the high-purity product required for its demanding applications. NINGBO INNO PHARMCHEM CO.,LTD. leverages advanced manufacturing techniques from our facilities in China to produce N-Carbobenzyloxy-L-aspartic acid that meets rigorous international quality standards.
The principal utility of N-Carbobenzyloxy-L-aspartic acid lies in its role as a building block for peptides. In peptide synthesis, controlling the reactivity of functional groups is paramount. The Cbz group on the alpha-amino group of aspartic acid allows for controlled peptide bond formation. After the coupling reaction, the Cbz group can be efficiently removed, often by catalytic hydrogenation, to allow for subsequent chain elongation. This method is fundamental to creating biologically active peptides and proteins.
As a trusted source for fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. offers N-Carbobenzyloxy-L-aspartic acid to researchers and industries worldwide. We understand the importance of reliable sourcing and consistent quality for critical intermediates like this. If you are looking to buy N-Carbobenzyloxy-L-aspartic acid, our company provides a dependable supply chain, competitive pricing, and excellent technical support. Our commitment as a manufacturer in China ensures that you receive a product that aligns with your project's exacting requirements.
N-Carbobenzyloxy-L-aspartic acid, also known as Z-Asp-OH, is a derivative of L-aspartic acid where the amino group is protected by the carbobenzyloxy (Cbz) moiety. This protection is crucial for preventing premature reactions and ensuring selectivity during complex multi-step syntheses. The compound typically presents as a white fine crystalline powder, with a melting point often cited around 117-119 °C. Its molecular formula is C12H13NO6, and it has a molecular weight of approximately 267.23 g/mol.
The synthesis of N-Carbobenzyloxy-L-aspartic acid is a well-established process. It typically begins with L-Aspartic acid, which is reacted with Benzyl chloroformate (Cbz-Cl) in an aqueous alkaline medium. This reaction selectively protects the alpha-amino group. Careful control of reaction conditions, followed by purification steps, yields the high-purity product required for its demanding applications. NINGBO INNO PHARMCHEM CO.,LTD. leverages advanced manufacturing techniques from our facilities in China to produce N-Carbobenzyloxy-L-aspartic acid that meets rigorous international quality standards.
The principal utility of N-Carbobenzyloxy-L-aspartic acid lies in its role as a building block for peptides. In peptide synthesis, controlling the reactivity of functional groups is paramount. The Cbz group on the alpha-amino group of aspartic acid allows for controlled peptide bond formation. After the coupling reaction, the Cbz group can be efficiently removed, often by catalytic hydrogenation, to allow for subsequent chain elongation. This method is fundamental to creating biologically active peptides and proteins.
As a trusted source for fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. offers N-Carbobenzyloxy-L-aspartic acid to researchers and industries worldwide. We understand the importance of reliable sourcing and consistent quality for critical intermediates like this. If you are looking to buy N-Carbobenzyloxy-L-aspartic acid, our company provides a dependable supply chain, competitive pricing, and excellent technical support. Our commitment as a manufacturer in China ensures that you receive a product that aligns with your project's exacting requirements.
Perspectives & Insights
Nano Explorer 01
“In peptide synthesis, controlling the reactivity of functional groups is paramount.”
Data Catalyst One
“The Cbz group on the alpha-amino group of aspartic acid allows for controlled peptide bond formation.”
Chem Thinker Labs
“After the coupling reaction, the Cbz group can be efficiently removed, often by catalytic hydrogenation, to allow for subsequent chain elongation.”